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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Does TRT Really Improve Sex Drive and Function in Older Men?
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<blockquote data-quote="madman" data-source="post: 192732" data-attributes="member: 13851"><p><strong>*<strong><u> TRT ameliorates erectile dysfunction by 2-3 points of IIEF-EFD that is at least one-half of the effect of any PDE5i.</u> </strong></strong><u><strong>In other words, TRT per se is effective in treating only a mild ED but ineffective in more severe forms of the same disorde</strong></u><strong>r. <u>This small effect is even attenuated in subjects with metabolic derangements, as in obesity and T2DM, most probably because the cardiovascular and neurological problems associated with these conditions bury the positive effect of TRT</u>. </strong></p><p><strong></strong></p><p><strong>*<strong>Effects of TRT on sexual desire are, in our opinion, more clinically meaningful for several reasons. <u>First, more than 20% of subjects consulting for sexual dysfunction in our andrology service have low T (<12 nmol/L)</u>. <u>Of those, nearly one-half has reduced sexual desire</u>. <u>Considering that there are no specific treatments for reduced sexual desire, apart from removing the underlying condition, TRT is a clinically meaningful option in hypogonadal subjects for improving libido</u>. <u>The more severe the T deficiency, the more evident the effect of TRT</u>. <u>In contrast, the effect is almost null in eugonadal individuals</u>.</strong></strong></p></blockquote><p></p>
[QUOTE="madman, post: 192732, member: 13851"] [B]*[B][U] TRT ameliorates erectile dysfunction by 2-3 points of IIEF-EFD that is at least one-half of the effect of any PDE5i.[/U] [/B][/B][U][B]In other words, TRT per se is effective in treating only a mild ED but ineffective in more severe forms of the same disorde[/B][/U][B]r. [U]This small effect is even attenuated in subjects with metabolic derangements, as in obesity and T2DM, most probably because the cardiovascular and neurological problems associated with these conditions bury the positive effect of TRT[/U]. *[B]Effects of TRT on sexual desire are, in our opinion, more clinically meaningful for several reasons. [U]First, more than 20% of subjects consulting for sexual dysfunction in our andrology service have low T (<12 nmol/L)[/U]. [U]Of those, nearly one-half has reduced sexual desire[/U]. [U]Considering that there are no specific treatments for reduced sexual desire, apart from removing the underlying condition, TRT is a clinically meaningful option in hypogonadal subjects for improving libido[/U]. [U]The more severe the T deficiency, the more evident the effect of TRT[/U]. [U]In contrast, the effect is almost null in eugonadal individuals[/U].[/B][/B] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Does TRT Really Improve Sex Drive and Function in Older Men?
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