Reply to thread

Yes, I agree I am not a strict believer in following the blood work vs. the  subjective symptoms but my quick opinion was based on your numbers which are very good.  But the HCG monotherapy is still not a natural pattern of hormone production, is it? thus it is possible that  the pattern of T output is less than ideal?  It can be an issue with TRT (roller-coaster) as well.   Since you are already diagnosed secondary hypo perhaps you could try and see how you do.  I certainly don't see much risk in it (unless you have another issue with your health that is being overlooked).  


Another problem, hard to diagnose, is stress related CNS exhaustion (more vulnerable as we age - similar to chronic over-training), which too much T can aggravate. I know you said you looked into adrenal function, I'm not sure it always shows up there - I would look at resting heart rate, grip strength, and HRV as indicators. Certainly sex drive is also affected negatively. 


As young men we seem able to adapt to high volumes of exercise and or hormones with mostly good results but in mid-life and older too much can tip us over the edge much easier than when we were young.


TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Back
Top