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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Does Shutting Down LH with Testosterone Have Negative Effects?
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<blockquote data-quote="Henry" data-source="post: 84848" data-attributes="member: 2067"><p>I was on another site (I'm not sure if I can mention other sites here so I'll just play it safe and quote the question and response) and someone asked a question about the downsides of TRT. Here is the question:</p><p> </p><p><span style="color: #00000A">"Is this true: there are countless secondary metabolic/hormonal pathways which get affected and down-regulated from long term HPTA suppression. Neurotransmitter balance, digestive health and bacteria, skin health, enzymatic function and expression amkng many other things take a hit."</span></p><p></p><p>and this was one of the responses:</p><p></p><p><span style="color: #00000A">"It's absolutely true. You lose both LH and GnRH. LH receptors exist all over the body. Your body loses control of its hormones and to lower them during sickness and sleep. You completely lose and destroy diurnal rythym (the natural state of low/high testosterone during night/day) which allows androgen receptors to resensitize overnight. You have to sleep with your T levels raging as if it was morning. The body normally spikes them along with cortisol to "wake you up," but TRT never gives the body a break. Since you aren't making your own testosterone anymore, many of the pathways towards testosterone start to "overflow" since they aren't being used anymore.</span></p><p><span style="color: #00000A">You completely break the natural work of and disrupt your pituitary and hypothalamus and they remain in a constant state of strain or disuse."</span></p><p> </p><p>I know that hCG is a LH analog so that covers the loss of LH but what about the rest of what was said. Is all this true or just broscience?</p></blockquote><p></p>
[QUOTE="Henry, post: 84848, member: 2067"] I was on another site (I'm not sure if I can mention other sites here so I'll just play it safe and quote the question and response) and someone asked a question about the downsides of TRT. Here is the question: [COLOR=#00000A][FONT=Helvetica]"Is this true: there are countless secondary metabolic/hormonal pathways which get affected and down-regulated from long term HPTA suppression. Neurotransmitter balance, digestive health and bacteria, skin health, enzymatic function and expression amkng many other things take a hit."[/FONT][/COLOR] and this was one of the responses: [COLOR=#00000A][FONT=Helvetica]"It's absolutely true. You lose both LH and GnRH. LH receptors exist all over the body. Your body loses control of its hormones and to lower them during sickness and sleep. You completely lose and destroy diurnal rythym (the natural state of low/high testosterone during night/day) which allows androgen receptors to resensitize overnight. You have to sleep with your T levels raging as if it was morning. The body normally spikes them along with cortisol to "wake you up," but TRT never gives the body a break. Since you aren't making your own testosterone anymore, many of the pathways towards testosterone start to "overflow" since they aren't being used anymore.[/FONT][/COLOR] [COLOR=#00000A][FONT=Helvetica]You completely break the natural work of and disrupt your pituitary and hypothalamus and they remain in a constant state of strain or disuse."[/FONT][/COLOR] I know that hCG is a LH analog so that covers the loss of LH but what about the rest of what was said. Is all this true or just broscience? [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Does Shutting Down LH with Testosterone Have Negative Effects?
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