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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Does SHBG affect the apparent half-lives of testosterone esters?
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<blockquote data-quote="Cataceous" data-source="post: 139473" data-attributes="member: 38109"><p>Yes, there are really two apparent half-lives at work, one for the absorption from the injected depot, which is different for different esters and formulations. The other half-life is associated with the clearance of testosterone, and is short, from minutes to hours. What can be confusing is that the two half-lives together create the serum testosterone levels we measure. My point with this thread is that SHBG can influence the clearance half-life pretty strongly, but in our serum measurements the longer ester half-life is dominant and controls the relative amplitudes, while the clearance half-life can scale serum measurements up or down by a constant amount.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 139473, member: 38109"] Yes, there are really two apparent half-lives at work, one for the absorption from the injected depot, which is different for different esters and formulations. The other half-life is associated with the clearance of testosterone, and is short, from minutes to hours. What can be confusing is that the two half-lives together create the serum testosterone levels we measure. My point with this thread is that SHBG can influence the clearance half-life pretty strongly, but in our serum measurements the longer ester half-life is dominant and controls the relative amplitudes, while the clearance half-life can scale serum measurements up or down by a constant amount. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Does SHBG affect the apparent half-lives of testosterone esters?
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