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Figure 1 Circadian rhythm of: (A), serum TT; (B) serum sex hormone-binding globulin (SHBG); (C) serum total proteins; (D) serum non-SHBG bound T (method of Plymate et al. (125)) of 10 young healthy men (closed square symbols with dispersion indices), mean age 27.3 years, and 10 elderly men (open circle symbols with dispersion indices), mean age 70.7 years—all nonsmokers, nonalcohol abusers, nonmedicated, and all within 10% ideal body weight. Black and white shading of the horizontal bar shown at bottom of each graph represent, respectively, presumed sleep and wake spans of the cohorts of the young and elderly male participants. Time is indicated in military form; 06:00 h=6 AM and 18:00 h=6 PM. Adapted, with permission, from Plymate SR, et al., 1989 (124).

[ATTACH=full]26653[/ATTACH]

[ATTACH=full]26654[/ATTACH]


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