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Thyroid, Pregnenolone, Progesterone, DHEA, etc
Thyroid, DHEA, Pregnenolone, Progesterone, etc
Does Iodine matter while on NDT?
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<blockquote data-quote="Marco N Cognito" data-source="post: 155156" data-attributes="member: 13"><p>My FT3 and FT4 have always shown normal or high normal while rT3 has never been less than mid range and TSH high normal since day one and no matter how much T3 I was taking whether NDT or straight. I am looking at several factors as to why this is and still don't have an answer. But here are some of the bad actors that may be the culprits that can cause cellular hypothyroidism (read more about that here: <a href="http://americannutritionassociation.org/newsletter/hypothyroidism" target="_blank">Hypothyroidism | American Nutrition Association</a>) that all affect T3 transport on a cellular level:</p><p></p><p><strong>1) methylation defect which impairs iron metabolism (I am +/+ for MTHFR C677T, the bad one)</strong></p><p><strong>2) cortisol (too high or too low can impair cellular T3 transport)</strong></p><p><strong>3) micronutrient deficiency (i.e. selenium, D, methyl donors, etc.)</strong></p><p><strong>4) genetic deiodinase polymorphisms that prevent adequate T4-T3 conversion (I have several)</strong></p><p><strong>5) Iron Deficiency Anemia & Hypoferritinemia without anemia</strong></p><p></p><p>Also - it's not only too much T4 that will cause a rise in rT3, but too much T3 will cause the same in those with one or more of the above issues.</p></blockquote><p></p>
[QUOTE="Marco N Cognito, post: 155156, member: 13"] My FT3 and FT4 have always shown normal or high normal while rT3 has never been less than mid range and TSH high normal since day one and no matter how much T3 I was taking whether NDT or straight. I am looking at several factors as to why this is and still don't have an answer. But here are some of the bad actors that may be the culprits that can cause cellular hypothyroidism (read more about that here: [URL='http://americannutritionassociation.org/newsletter/hypothyroidism']Hypothyroidism | American Nutrition Association[/URL]) that all affect T3 transport on a cellular level: [B]1) methylation defect which impairs iron metabolism (I am +/+ for MTHFR C677T, the bad one) 2) cortisol (too high or too low can impair cellular T3 transport) 3) micronutrient deficiency (i.e. selenium, D, methyl donors, etc.) 4) genetic deiodinase polymorphisms that prevent adequate T4-T3 conversion (I have several) 5) Iron Deficiency Anemia & Hypoferritinemia without anemia[/B] Also - it's not only too much T4 that will cause a rise in rT3, but too much T3 will cause the same in those with one or more of the above issues. [/QUOTE]
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Thyroid, Pregnenolone, Progesterone, DHEA, etc
Thyroid, DHEA, Pregnenolone, Progesterone, etc
Does Iodine matter while on NDT?
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