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I can only speak to my experience. When my E2 was high, my acne was horrible. Now that I have better control of my E2 my acne problem has disappeared.

I remember when I tried pellets and my doctor overshot on the number of pellets and my T levels soared to 1600. My E2 also soared to over 100. My doctor would not put me on an aromatase inhibitor. My acne was worse than anytime since I was in high school for the next couple of months.

I switched to a T-cream about six weeks ago. I've only taken my anastrozole maybe twice in that time and can tell just by how I feel that my E2 is in range. Just wondering if the cream is going to help keep my hematocrits in range as well. I'm not due for labs for a while so this is based on how I feel.

J-

[QUOTE="JDieken, post: 145111, member: 16735"] I can only speak to my experience. When my E2 was high, my acne was horrible. Now that I have better control of my E2 my acne problem has disappeared. I remember when I tried pellets and my doctor overshot on the number of pellets and my T levels soared to 1600. My E2 also soared to over 100. My doctor would not put me on an aromatase inhibitor. My acne was worse than anytime since I was in high school for the next couple of months. I switched to a T-cream about six weeks ago. I've only taken my anastrozole maybe twice in that time and can tell just by how I feel that my E2 is in range. Just wondering if the cream is going to help keep my hematocrits in range as well. I'm not due for labs for a while so this is based on how I feel. J- [/QUOTE]

Verification

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038