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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Does applying T cream on hairless skin reduce DHT production?
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<blockquote data-quote="RobRoy" data-source="post: 255070" data-attributes="member: 42893"><p>Your DHT is going to go up no matter where you apply the cream but there is more five alpha reductase in the scrotal skin than other areas. So yes the DHT that you will measure will be less applying to skin that has less 5 alpha reductase. But what do you measure is not what is at the tissue level. No matter where you apply the cream you're going to increase DHT at the tissue level to a saturation point. Just like if you gave someone injections you're still going to raise DHT at the tissue level. You can measure serum levels of DHT 10 times normal but at the tissue level the DHT is going to remain constant because they have homeostatic mechanisms that tightly control intracellular levels. It's literally useless to measure DHT levels. And one of the side effects of testosterone no matter how you get it is increased hair when you don't want it and decreased hair where you do want it</p></blockquote><p></p>
[QUOTE="RobRoy, post: 255070, member: 42893"] Your DHT is going to go up no matter where you apply the cream but there is more five alpha reductase in the scrotal skin than other areas. So yes the DHT that you will measure will be less applying to skin that has less 5 alpha reductase. But what do you measure is not what is at the tissue level. No matter where you apply the cream you're going to increase DHT at the tissue level to a saturation point. Just like if you gave someone injections you're still going to raise DHT at the tissue level. You can measure serum levels of DHT 10 times normal but at the tissue level the DHT is going to remain constant because they have homeostatic mechanisms that tightly control intracellular levels. It's literally useless to measure DHT levels. And one of the side effects of testosterone no matter how you get it is increased hair when you don't want it and decreased hair where you do want it [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Does applying T cream on hairless skin reduce DHT production?
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