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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Does anything lower testosterone when on TRT?
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<blockquote data-quote="Cataceous" data-source="post: 159180" data-attributes="member: 38109"><p>Under TRT, estrogen conversion, or lack thereof, has a very minor effect on testosterone levels. This is because one ng/dL of testosterone creates about 10 pg/mL of estradiol. So while 50 pg/mL is a lot of estradiol, it represents only about 5 ng/dL of testosterone, which is insignificant.</p><p></p><p>Regarding the original question, you'd be looking at things that change the absorption rate of testosterone. One might speculate that the enhanced blood/fluid flow caused by exercise could enhance absorption of injected testosterone. If true this would result in a little higher free and total testosterone.</p><p></p><p>An important point is that the excretion rate is governed by the absorption rate, at least over any reasonable time period, say on the order of hours. One study I came across suggests that exercise decreases the metabolic clearance rate of testosterone. Assuming this is true and unrelated to SHBG, then such variation would result in an increase in free and total testosterone, with each going higher, at least temporarily, to again make excretion match absorption.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 159180, member: 38109"] Under TRT, estrogen conversion, or lack thereof, has a very minor effect on testosterone levels. This is because one ng/dL of testosterone creates about 10 pg/mL of estradiol. So while 50 pg/mL is a lot of estradiol, it represents only about 5 ng/dL of testosterone, which is insignificant. Regarding the original question, you'd be looking at things that change the absorption rate of testosterone. One might speculate that the enhanced blood/fluid flow caused by exercise could enhance absorption of injected testosterone. If true this would result in a little higher free and total testosterone. An important point is that the excretion rate is governed by the absorption rate, at least over any reasonable time period, say on the order of hours. One study I came across suggests that exercise decreases the metabolic clearance rate of testosterone. Assuming this is true and unrelated to SHBG, then such variation would result in an increase in free and total testosterone, with each going higher, at least temporarily, to again make excretion match absorption. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Does anything lower testosterone when on TRT?
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