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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Doctor will not perform surgery
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<blockquote data-quote="Cataceous" data-source="post: 156842" data-attributes="member: 38109"><p>I am pretty sure that the interaction between testosterone and aromatase occurs only when the testosterone is free. But don't think of SHBG as a permanent jail. It's a reservoir that releases testosterone when free levels drop.</p><p></p><p></p><p>It's plausible that there would be focal high-T spots at the injection sites. But in general the cleaving of testosterone from the ester occurs in the bloodstream. It's a slow and steady process, unless you happened to do an IV injection. Otherwise the absorption rate from the injected depots is driving everything (free T, etc.), and this is much slower than other processes.</p><p></p><p></p><p>As long as it's accurate, free T is more important than total. For those whose SHBG doesn't change much then total can have similar utility. Getting accurate free T is a matter of either paying for an equilibrium dialysis test or using the Tru-T calculator to get a good estimate from total T and SHBG.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 156842, member: 38109"] I am pretty sure that the interaction between testosterone and aromatase occurs only when the testosterone is free. But don't think of SHBG as a permanent jail. It's a reservoir that releases testosterone when free levels drop. It's plausible that there would be focal high-T spots at the injection sites. But in general the cleaving of testosterone from the ester occurs in the bloodstream. It's a slow and steady process, unless you happened to do an IV injection. Otherwise the absorption rate from the injected depots is driving everything (free T, etc.), and this is much slower than other processes. As long as it's accurate, free T is more important than total. For those whose SHBG doesn't change much then total can have similar utility. Getting accurate free T is a matter of either paying for an equilibrium dialysis test or using the Tru-T calculator to get a good estimate from total T and SHBG. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Doctor will not perform surgery
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