ExcelMale
Menu
Home
What's new
Latest activity
Forums
New posts
Search forums
What's new
New posts
Latest activity
Videos
Lab Tests
Doctor Finder
Buy Books
About Us
Men’s Health Coaching
Log in
Register
What's new
Search
Search
Search titles only
By:
New posts
Search forums
Menu
Log in
Register
Navigation
Install the app
Install
More options
Contact us
Close Menu
Forums
General Health & Fitness
Health & Wellness
Do you have restless leg syndrome? I understood from your eyes
JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding.
You are using an out of date browser. It may not display this or other websites correctly.
You should upgrade or use an
alternative browser
.
Reply to thread
Message
<blockquote data-quote="madman" data-source="post: 126339" data-attributes="member: 13851"><p><strong>Abstract </strong></p><p></p><p></p><p><strong>Purpose</strong></p><p>According to many studies in the literature, there is a<strong><span style="color: rgb(184, 49, 47)"> strong association between restless leg syndrome and dopaminergic dysfunction. Dopamine is also the major catecholamine in the retina and is also a possible transmitter of the amacrine and interplexiform cells.</span></strong> The aim of this study is to investigate the possible association between RLS and retinal thickness. </p><p></p><p><strong>Methods </strong></p><p>In this study, we included 33 patients who were diagnosed with idiopathic RLS according to the BInternational RLS Study Group^ criteria and 31 healthy subjects. All the patients and controls underwent routine ophthalmologic examination and had spectral-domain optical coherence tomography (OCT) performed. We compared the retinal thickness of the patients and control subjects. </p><p></p><p><strong>Results </strong></p><p>In the RLS group, foveal thickness was thinner then controls. Also, only inferior, superior, and temporal quadrant retina nerve fiber layer (RNFL) thickness were significantly thinner in the RLS group. The parafoveal ganglion cell complex (GCC) in the superior temporal, inferior temporal, inferior nasal quadrant, and perifoveal superior nasal thickness was also significantly thinner in the patient group. Pearson correlation analyses showed that there were statistically significant negative correlations between disease duration and macular GCC and RNFL thickness. Negative correlations were also detected between parafoveal superior, temporal, inferior and nasal macular thickness, parafoveal superior nasal, inferior temporal GCC thickness, and perifoveal superior nasal GCC thickness and disease duration.</p><p></p><p><strong>Conclusion </strong></p><p>According to our results; most retinal layers are thinner in RLS patients, so it can be considered that OCT has a predictive value for progression of RLS.</p><p></p><p></p><p></p><p></p><p></p><p></p><p>In conclusion; in the recent period the use of OCT to monitor progression and prognosis of neurodegenerative diseases like PD has become a focus. There has been limited research into the retinal changes in RLS, known to be related to dopamine metabolism. In our study, we showed the presence of some retinal changes in RLS patients and that these are correlated with the duration and severity of disease. Analysis of the macular thickness and retinal nerve fiber layer with OCT can be beneficial in follow-up of RLS progression.</p></blockquote><p></p>
[QUOTE="madman, post: 126339, member: 13851"] [B]Abstract [/B] [B]Purpose[/B] According to many studies in the literature, there is a[B][COLOR=rgb(184, 49, 47)] strong association between restless leg syndrome and dopaminergic dysfunction. Dopamine is also the major catecholamine in the retina and is also a possible transmitter of the amacrine and interplexiform cells.[/COLOR][/B] The aim of this study is to investigate the possible association between RLS and retinal thickness. [B]Methods [/B] In this study, we included 33 patients who were diagnosed with idiopathic RLS according to the BInternational RLS Study Group^ criteria and 31 healthy subjects. All the patients and controls underwent routine ophthalmologic examination and had spectral-domain optical coherence tomography (OCT) performed. We compared the retinal thickness of the patients and control subjects. [B]Results [/B] In the RLS group, foveal thickness was thinner then controls. Also, only inferior, superior, and temporal quadrant retina nerve fiber layer (RNFL) thickness were significantly thinner in the RLS group. The parafoveal ganglion cell complex (GCC) in the superior temporal, inferior temporal, inferior nasal quadrant, and perifoveal superior nasal thickness was also significantly thinner in the patient group. Pearson correlation analyses showed that there were statistically significant negative correlations between disease duration and macular GCC and RNFL thickness. Negative correlations were also detected between parafoveal superior, temporal, inferior and nasal macular thickness, parafoveal superior nasal, inferior temporal GCC thickness, and perifoveal superior nasal GCC thickness and disease duration. [B]Conclusion [/B] According to our results; most retinal layers are thinner in RLS patients, so it can be considered that OCT has a predictive value for progression of RLS. In conclusion; in the recent period the use of OCT to monitor progression and prognosis of neurodegenerative diseases like PD has become a focus. There has been limited research into the retinal changes in RLS, known to be related to dopamine metabolism. In our study, we showed the presence of some retinal changes in RLS patients and that these are correlated with the duration and severity of disease. Analysis of the macular thickness and retinal nerve fiber layer with OCT can be beneficial in follow-up of RLS progression. [/QUOTE]
Insert quotes…
Verification
Post reply
Share this page
Facebook
Twitter
Reddit
Pinterest
Tumblr
WhatsApp
Email
Share
Link
Sponsors
Forums
General Health & Fitness
Health & Wellness
Do you have restless leg syndrome? I understood from your eyes
This site uses cookies to help personalise content, tailor your experience and to keep you logged in if you register.
By continuing to use this site, you are consenting to our use of cookies.
Accept
Learn more…
Top