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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Do we really need LH, or HCG, to convert Pregnenolone to downstream Hormones?
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<blockquote data-quote="Gianluca" data-source="post: 147462" data-attributes="member: 15469"><p>[USER=3]@Nelson Vergel[/USER], I'm going to tag you again on this. I just watched the video on the link below and enjoyed it. Looking really forward for the Thyroid one. In the video you mentioned again LH is needed to convert Pregnenolone to downstream hormones. </p><p>[MEDIA=youtube]QPhGFK_o7U4:1376[/MEDIA] </p><p></p><p>We had a quick chat on another post about the same subject, where I mentioned that despite I was not using HCG for several months and having my LH suppressed due to TRT, my Progesterone was at high end of the scale, by using 100mg Prenenolone RX. I recently read this study on Pregnenolone where it states that enzymes are responsible for the conversion of Pregnenolone to downstream hormones, here some of the text:</p><p></p><p>"For instance, the presence of the mitochondrial cholesterol transport and metabolism machinery, including steroidogenic acute regulatory protein (STAR) and CYP11A1, suggests that adipose and intestine tissues may have the ability to synthesize PREG de novo [70,75]. <strong>Moreover, almost all the steroid-converting enzymes downstream of PREG have been discovered in mouse or human adipose and intestine tissue "</strong></p><p></p><p>My point is that if LH is needed for the conversion of downstream hormones, then all of those not using HCG should have Cortisol issues, low Aldosterone issue, and many other.</p><p></p><p>Attached is the full study</p></blockquote><p></p>
[QUOTE="Gianluca, post: 147462, member: 15469"] [USER=3]@Nelson Vergel[/USER], I'm going to tag you again on this. I just watched the video on the link below and enjoyed it. Looking really forward for the Thyroid one. In the video you mentioned again LH is needed to convert Pregnenolone to downstream hormones. [MEDIA=youtube]QPhGFK_o7U4:1376[/MEDIA] We had a quick chat on another post about the same subject, where I mentioned that despite I was not using HCG for several months and having my LH suppressed due to TRT, my Progesterone was at high end of the scale, by using 100mg Prenenolone RX. I recently read this study on Pregnenolone where it states that enzymes are responsible for the conversion of Pregnenolone to downstream hormones, here some of the text: "For instance, the presence of the mitochondrial cholesterol transport and metabolism machinery, including steroidogenic acute regulatory protein (STAR) and CYP11A1, suggests that adipose and intestine tissues may have the ability to synthesize PREG de novo [70,75]. [B]Moreover, almost all the steroid-converting enzymes downstream of PREG have been discovered in mouse or human adipose and intestine tissue "[/B] My point is that if LH is needed for the conversion of downstream hormones, then all of those not using HCG should have Cortisol issues, low Aldosterone issue, and many other. Attached is the full study [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Do we really need LH, or HCG, to convert Pregnenolone to downstream Hormones?
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