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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Do I need to come off TRT to use HCG for fertility?
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<blockquote data-quote="madman" data-source="post: 146294" data-attributes="member: 13851"><p><span style="font-size: 26px"><strong>Low-dose hCG can prevent sterility in men prescribed testosterone (<span style="color: rgb(184, 49, 47)">2019</span>)</strong></span></p><p></p><p>pg 1-3</p><p></p><p><a href="https://www.healio.com/endocrinology/reproduction-androgen-disorders/news/online/%7B027a4c7b-74f0-4f3a-a30f-0c24bd4365bd%7D/low-dose-hcg-can-prevent-sterility-in-men-prescribed-testosterone" target="_blank">Low-dose hCG can prevent sterility in men prescribed testosterone</a></p><p></p><p></p><p></p><p></p><p></p><p><strong>Strategy for clinicians</strong></p><p></p><p><strong>To <span style="color: rgb(184, 49, 47)">maintain fertility in men with hypogonadism prescribed testosterone</span>, Lipshultz said, <span style="color: rgb(184, 49, 47)">clinicians should first insist on a semen analysis before beginning testosterone treatment.</span></strong></p><p></p><p><strong>“<span style="color: rgb(184, 49, 47)">Patients</span> need to realize that <span style="color: rgb(184, 49, 47)">2% of all men are sterile</span>,” Lipshultz said.</strong> <strong>“We need to know where the individual is <span style="color: rgb(184, 49, 47)">before we introduce testosterone</span> because our <span style="color: rgb(184, 49, 47)">endpoint </span>may not be able to be any better than <span style="color: rgb(184, 49, 47)">pre-treatment level.</span>”</strong></p><p></p><p>If the man desires a future pregnancy, the clinician should prescribe hCG concurrent with testosterone therapy, typically at 500 U subcutaneous three times per week or 1,500 U once weekly if the patient wishes only to prevent testicular atrophy. The patient should cycle off of testosterone twice yearly, at a rate of 3,000 U three times per week for 4 weeks, adding 25 mg daily clomiphene therapy during that period, Lipshultz said. However, for men desiring a pregnancy, 3,000 U hCG three times per week should be prescribed in addition to clomiphene therapy. Clinicians should check the patient’s follicle-stimulating hormone (FSH) level and conduct a semen analysis after 4 months for men desiring pregnancy; if the FSH level is not sufficiently elevated, the clinician should discontinue clomiphene and instead introduce FSH concurrent with the hCG, he said.</p><p></p><p><strong><span style="color: rgb(184, 49, 47)">“To date, we have not had any patients who did not return to baseline,”</span></strong> <strong>Lipshultz said, referring to the regimen.</strong> – <em>by Regina Schaffer</em></p></blockquote><p></p>
[QUOTE="madman, post: 146294, member: 13851"] [SIZE=26px][B]Low-dose hCG can prevent sterility in men prescribed testosterone ([COLOR=rgb(184, 49, 47)]2019[/COLOR])[/B][/SIZE] pg 1-3 [URL='https://www.healio.com/endocrinology/reproduction-androgen-disorders/news/online/%7B027a4c7b-74f0-4f3a-a30f-0c24bd4365bd%7D/low-dose-hcg-can-prevent-sterility-in-men-prescribed-testosterone']Low-dose hCG can prevent sterility in men prescribed testosterone[/URL] [B]Strategy for clinicians[/B] [B]To [COLOR=rgb(184, 49, 47)]maintain fertility in men with hypogonadism prescribed testosterone[/COLOR], Lipshultz said, [COLOR=rgb(184, 49, 47)]clinicians should first insist on a semen analysis before beginning testosterone treatment.[/COLOR][/B] [B]“[COLOR=rgb(184, 49, 47)]Patients[/COLOR] need to realize that [COLOR=rgb(184, 49, 47)]2% of all men are sterile[/COLOR],” Lipshultz said.[/B] [B]“We need to know where the individual is [COLOR=rgb(184, 49, 47)]before we introduce testosterone[/COLOR] because our [COLOR=rgb(184, 49, 47)]endpoint [/COLOR]may not be able to be any better than [COLOR=rgb(184, 49, 47)]pre-treatment level.[/COLOR]”[/B] If the man desires a future pregnancy, the clinician should prescribe hCG concurrent with testosterone therapy, typically at 500 U subcutaneous three times per week or 1,500 U once weekly if the patient wishes only to prevent testicular atrophy. The patient should cycle off of testosterone twice yearly, at a rate of 3,000 U three times per week for 4 weeks, adding 25 mg daily clomiphene therapy during that period, Lipshultz said. However, for men desiring a pregnancy, 3,000 U hCG three times per week should be prescribed in addition to clomiphene therapy. Clinicians should check the patient’s follicle-stimulating hormone (FSH) level and conduct a semen analysis after 4 months for men desiring pregnancy; if the FSH level is not sufficiently elevated, the clinician should discontinue clomiphene and instead introduce FSH concurrent with the hCG, he said. [B][COLOR=rgb(184, 49, 47)]“To date, we have not had any patients who did not return to baseline,”[/COLOR][/B] [B]Lipshultz said, referring to the regimen.[/B] – [I]by Regina Schaffer[/I] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Do I need to come off TRT to use HCG for fertility?
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