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I've had an up and down experience trying to dial in my numbers on my TRT and adex dosage and have crashed my E2 down to 7pg/nL a couple times and I'm pretty sure I know what that feels like.  This time I've crashed it even further or I'm experiencing something new.  For reference my test dose is 80mg twice a week and I was taking .25mg adex twice a week.  That still may have been too much.  I haven't taken any in a couple weeks since the dizziness and out of it feeling started, and when that hits usually between 8am and 4pm, my skin feels strange and my teeth also.  I also have horrible anxiety during this which makes me think it's E2 related because when my E2 is low, I have panic-symptoms from 8am to mid-day.  I've also considered maybe it's the non-GMO testosterone cypionate (contains grapeseed oil) from a compounding pharmacy I started 8 weeks ago.  Prior to that I used the normal stuff you get from any pharmacy (cottonseed oil).  I'm in touch with my doctor about this now, but I wanted to see if anyone else had issues like this.  I thought it might be DHEA so I stopped taking it Friday and thought I was getting a little better until today.  Today has been terrible.  Anyone have any thoughts?  Thanks.


TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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