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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Discrepancies in Four Algorithms for the Calculation of Free and Bioavailable T
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<blockquote data-quote="madman" data-source="post: 269782" data-attributes="member: 13851"><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/testosterone-assays.27661/[/URL]</p><p></p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/direct-measurements-of-free-hormones-using-mass-spectrometry-based-methods.28144/[/URL]</p><p></p><p><strong>IMPACT STATEMENT</strong></p><p></p><p><em><strong>Measurement of free hormone (FH) concentrations in biological samples presents a challenge to the clinical laboratory. <u>FH concentrations are generally very low, requiring the use of sensitive and specific techniques</u>. <u>Furthermore, special attention must be placed on the equilibrium between free and protein-bound hormones when separating and analyzing in vitro</u>. This review will enhance the readers’ understanding of the current state of mass spectrometry-based methods for the measurement of FHs. The advantages and disadvantages of different separation techniques and sample preparation methods are discussed, as well as clinical conditions in which measurement of FH is warranted.</strong></em></p></blockquote><p></p>
[QUOTE="madman, post: 269782, member: 13851"] [URL unfurl="true"]https://www.excelmale.com/forum/threads/testosterone-assays.27661/[/URL] [URL unfurl="true"]https://www.excelmale.com/forum/threads/direct-measurements-of-free-hormones-using-mass-spectrometry-based-methods.28144/[/URL] [B]IMPACT STATEMENT[/B] [I][B]Measurement of free hormone (FH) concentrations in biological samples presents a challenge to the clinical laboratory. [U]FH concentrations are generally very low, requiring the use of sensitive and specific techniques[/U]. [U]Furthermore, special attention must be placed on the equilibrium between free and protein-bound hormones when separating and analyzing in vitro[/U]. This review will enhance the readers’ understanding of the current state of mass spectrometry-based methods for the measurement of FHs. The advantages and disadvantages of different separation techniques and sample preparation methods are discussed, as well as clinical conditions in which measurement of FH is warranted.[/B][/I] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Discrepancies in Four Algorithms for the Calculation of Free and Bioavailable T
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