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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Did estrogen crash cause me permanent symptoms of low dopamine?
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<blockquote data-quote="keigwin" data-source="post: 79992" data-attributes="member: 16350"><p>I don't think I ever did adjust to the lower dopamine levels, because after seeing my labs from 5/17/17 I went back on bupropion SR, albeit at a smaller dosage (was 150mg/day, then zero, then 75 mg/day). By 6/14/17 my prolactin had lowered nearly 10%. After 7/2/17 when I started the AI it's hard to say whether the continued lowering of prolactin was due to increased dopamine or lower estrogen, but I know it takes time for a dopamine reuptake inhibitor to fully take effect so certainly it must have been playing a role. Restoring 'homeostasis' as you say.</p><p></p><p></p><p></p><p>Again, it's hard to disentangle the effect of lower prolactin vs. lower E2 on my libido, but I can say that before the dopamine incident I still had a libido, though not a strong one. This points to prolactin as the ultimate libido-killer, which makes sense when you consider its role in killing post-orgasm libido in men.</p><p></p><p>To answer your question, my E2 readings were and 43 pg/mL (<= 39) on 2/17/15 and 41.5 pg/mL (7.6-42.6) on 5/17/17, using the non-sensitive test. Those are my only pre-AI references. I've been testing about every 4 weeks since starting anastrozole, trying to home in on the ideal dosage for me. I definitely wouldn't recommend playing with an AI without frequent testing, as it seems pretty easy to go from feeling bad (high E2) to good to bad again (low E2).</p><p></p><p>I wish I could say something helpful about your situation, but since I'm not on testosterone at the moment I have no experience to draw upon. I do wish you the best, though!</p></blockquote><p></p>
[QUOTE="keigwin, post: 79992, member: 16350"] I don't think I ever did adjust to the lower dopamine levels, because after seeing my labs from 5/17/17 I went back on bupropion SR, albeit at a smaller dosage (was 150mg/day, then zero, then 75 mg/day). By 6/14/17 my prolactin had lowered nearly 10%. After 7/2/17 when I started the AI it's hard to say whether the continued lowering of prolactin was due to increased dopamine or lower estrogen, but I know it takes time for a dopamine reuptake inhibitor to fully take effect so certainly it must have been playing a role. Restoring 'homeostasis' as you say. Again, it's hard to disentangle the effect of lower prolactin vs. lower E2 on my libido, but I can say that before the dopamine incident I still had a libido, though not a strong one. This points to prolactin as the ultimate libido-killer, which makes sense when you consider its role in killing post-orgasm libido in men. To answer your question, my E2 readings were and 43 pg/mL (<= 39) on 2/17/15 and 41.5 pg/mL (7.6-42.6) on 5/17/17, using the non-sensitive test. Those are my only pre-AI references. I've been testing about every 4 weeks since starting anastrozole, trying to home in on the ideal dosage for me. I definitely wouldn't recommend playing with an AI without frequent testing, as it seems pretty easy to go from feeling bad (high E2) to good to bad again (low E2). I wish I could say something helpful about your situation, but since I'm not on testosterone at the moment I have no experience to draw upon. I do wish you the best, though! [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Did estrogen crash cause me permanent symptoms of low dopamine?
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