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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Dialing in right dosage/regiment on TRT
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<blockquote data-quote="madman" data-source="post: 185130" data-attributes="member: 13851"><p>Need to post reference ranges.</p><p></p><p>Seeing as you are on once-weekly injections (100mg/week) with a trough TT 524 ng/dl and SHBG on the higher end than your FT levels would be far from optimal.</p><p></p><p>Although your peak TT/FT/e2 levels will be much higher post-injection the downfall of injecting higher doses of T once weekly is that there will be a big difference in the peak--->trough as your levels will be very high post-injection only to end up much lower come weeks end and your blood levels will not be as stable throughout the week which can have a yo-yo effect on ones mood/energy/libido/erectile function/overall well-being.</p><p></p><p>Would have been far better off splitting the dose 100 mg/week and injecting 50 mg twice weekly (every 3.5 days) as not only would blood levels be more stable but you minimize the peak--->trough levels and could very well have achieved better T levels.</p><p></p><p>That said you will most likely need a slight dose increase but even then I would not jump from 100--->140 mg/week as 20 mg/week increase will have a big impact on increasing your TT/FT level and you would be better off injecting 120mg/week (60 mg every 3.5 days).</p><p></p><p>Start low and go slow is key.</p><p></p><p>Most men do well with FT in the 20-30 ng/dL range.</p><p></p><p>What is critical is to make sure when testing your FT that you get the most accurate assay such as the gold standard Equilibrium Dialysis or Ultrafiltration (next best) if you truly want to know where your FT level sits. </p><p></p><p>Although TT is important to know FT is what truly matters as it is the active unbound fraction of testosterone responsible for the beneficial effects.</p><p></p><p>You also need to keep in mind that pre-trt your hematocrit was 45 and after 5 weeks on 100 mg/week protocol it jumped up to 50 which is a big increase.</p><p></p><p>Any time one uses exogenous testosterone it will result in driving up RBCs/hemoglobin/hematocrit and this will happen within the 1st month and can take anywhere from 9-12 months to reach peak levels.</p><p></p><p>Increasing your T dose will only drive up your levels further.</p></blockquote><p></p>
[QUOTE="madman, post: 185130, member: 13851"] Need to post reference ranges. Seeing as you are on once-weekly injections (100mg/week) with a trough TT 524 ng/dl and SHBG on the higher end than your FT levels would be far from optimal. Although your peak TT/FT/e2 levels will be much higher post-injection the downfall of injecting higher doses of T once weekly is that there will be a big difference in the peak--->trough as your levels will be very high post-injection only to end up much lower come weeks end and your blood levels will not be as stable throughout the week which can have a yo-yo effect on ones mood/energy/libido/erectile function/overall well-being. Would have been far better off splitting the dose 100 mg/week and injecting 50 mg twice weekly (every 3.5 days) as not only would blood levels be more stable but you minimize the peak--->trough levels and could very well have achieved better T levels. That said you will most likely need a slight dose increase but even then I would not jump from 100--->140 mg/week as 20 mg/week increase will have a big impact on increasing your TT/FT level and you would be better off injecting 120mg/week (60 mg every 3.5 days). Start low and go slow is key. Most men do well with FT in the 20-30 ng/dL range. What is critical is to make sure when testing your FT that you get the most accurate assay such as the gold standard Equilibrium Dialysis or Ultrafiltration (next best) if you truly want to know where your FT level sits. Although TT is important to know FT is what truly matters as it is the active unbound fraction of testosterone responsible for the beneficial effects. You also need to keep in mind that pre-trt your hematocrit was 45 and after 5 weeks on 100 mg/week protocol it jumped up to 50 which is a big increase. Any time one uses exogenous testosterone it will result in driving up RBCs/hemoglobin/hematocrit and this will happen within the 1st month and can take anywhere from 9-12 months to reach peak levels. Increasing your T dose will only drive up your levels further. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Dialing in right dosage/regiment on TRT
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