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Testosterone Replacement, Low T, HCG, & Beyond
When Testosterone Is Not Enough
Diagnostic Value of PCDU in Patients with Veno-occlusive ED
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<blockquote data-quote="madman" data-source="post: 199229" data-attributes="member: 13851"><p><strong><em>*The most common etiology of organic ED is vasculogenic ED. ED can be a sign of various underlying vascular disorders. <u>Endothelial dysfunction plays an important role in the pathophysiology of vasculogenic causes of ED</u>. <u>It commonly occurs as a result of insufficient synthesis, release, and response of endothelial NO</u>.[17] Hypercholesterolemia, hypertension, diabetes mellitus, smoking, and endothelial dysfunction due to aging are risk factors for ED because they cause arterial insufficiency.[18] In VOD, hypoxia caused by decreased corpora cavernosal oxygenation may reduce the levels of prostaglandin E1, which normally inhibits profibrotic cytokines that promote collagen deposition, replacing the smooth muscle and resulting in decreased elasticity of the penis.[19] Since the ratio of smooth muscle to collagen decreases and collagen content increases, the ability of the cavernosa to compress the subtunical veins decrease, causing corporal VOD.[20]</em></strong></p></blockquote><p></p>
[QUOTE="madman, post: 199229, member: 13851"] [B][I]*The most common etiology of organic ED is vasculogenic ED. ED can be a sign of various underlying vascular disorders. [U]Endothelial dysfunction plays an important role in the pathophysiology of vasculogenic causes of ED[/U]. [U]It commonly occurs as a result of insufficient synthesis, release, and response of endothelial NO[/U].[17] Hypercholesterolemia, hypertension, diabetes mellitus, smoking, and endothelial dysfunction due to aging are risk factors for ED because they cause arterial insufficiency.[18] In VOD, hypoxia caused by decreased corpora cavernosal oxygenation may reduce the levels of prostaglandin E1, which normally inhibits profibrotic cytokines that promote collagen deposition, replacing the smooth muscle and resulting in decreased elasticity of the penis.[19] Since the ratio of smooth muscle to collagen decreases and collagen content increases, the ability of the cavernosa to compress the subtunical veins decrease, causing corporal VOD.[20][/I][/B] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
When Testosterone Is Not Enough
Diagnostic Value of PCDU in Patients with Veno-occlusive ED
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