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Thyroid, Pregnenolone, Progesterone, DHEA, etc
Thyroid, DHEA, Pregnenolone, Progesterone, etc
DHEA supplements may exacerbate COVID-19
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<blockquote data-quote="Cataceous" data-source="post: 193733" data-attributes="member: 38109"><p>That's interesting. I wonder if the statement in <a href="https://pubmed.ncbi.nlm.nih.gov/9052415/" target="_blank">this work</a> has any relevance. "DHEA inhibition of G6PD was only found to occur at concentrations above 10 microM..." If that's microMoles per liter then it translates to around 300 mcg/dL, right at typical serum levels. <a href="https://www.researchgate.net/publication/259491858_Dehydroepiandrosterone_promotes_pulmonary_artery_relaxation_by_NADPH_oxidation-elicited_subunit_dimerization_of_Protein_Kinase_G_1a" target="_blank">This work</a> also seems to demonstrate significant effects at 10 microM, but not at 1 microM.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 193733, member: 38109"] That's interesting. I wonder if the statement in [URL='https://pubmed.ncbi.nlm.nih.gov/9052415/']this work[/URL] has any relevance. "DHEA inhibition of G6PD was only found to occur at concentrations above 10 microM..." If that's microMoles per liter then it translates to around 300 mcg/dL, right at typical serum levels. [URL='https://www.researchgate.net/publication/259491858_Dehydroepiandrosterone_promotes_pulmonary_artery_relaxation_by_NADPH_oxidation-elicited_subunit_dimerization_of_Protein_Kinase_G_1a']This work[/URL] also seems to demonstrate significant effects at 10 microM, but not at 1 microM. [/QUOTE]
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Thyroid, Pregnenolone, Progesterone, DHEA, etc
Thyroid, DHEA, Pregnenolone, Progesterone, etc
DHEA supplements may exacerbate COVID-19
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