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General Health & Fitness
Nutrition and Supplements
DHEA Supplements- Do They Work?
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<blockquote data-quote="Nelson Vergel" data-source="post: 1095" data-attributes="member: 3"><p>It has some effect on fat loss but it does not seem that great. I doubt that the pain and cramping you experience are due to the supplement but I suggest you consult your physician. Are you working out? Cramping can also be caused by calcium or other mineral deficiencies.</p><p></p><p>This is from examine.com</p><p></p><p>One study using 7-Keto in isolation at 200mg (100mg twice a day for 7 days) noted that, during a period of caloric restriction (800kcal less than regular intake), metabolic rate increased an average of 1.4% (total caloric expenditure a highly variable 21+/-115kcal) while placebo experienced a decrease in metabolic rate by 3.9% relative to baseline; this study was too short in duration to assess changes in weight.<a href="http://examine.com/supplements/7-Keto+DHEA/#ref36" target="_blank">[36]</a></p><p> In accessing the metabolic rate, 7-Keto supplementation appears to attenuate or reverse the decline in metabolic rate associated with caloric restriction</p><p>Studies conducted over a longer period of time note that 200mg (100mg twice daily) for 8 weeks in obese adults in combination with a weight loss diet (1800kcal mixed diet) and exercise program (3 days weeks cross training) noted that the loss in weight associated with placebo (0.97kg) was increased (2.88kg) as well as the fat loss (from 0.57% to 1.8%); no significant differences in dietary intake were reported.<a href="http://examine.com/supplements/7-Keto+DHEA/#ref27" target="_blank">[27]</a></p><p> Studies measuring weight loss associated with 7-keto note that supplementation results in more weight and fat loss over a period of time; both studies were paired with diet and exercise which may be prerequisites</p><p>Another trial (external funding source and confounded with <a href="http://examine.com/supplements/Asparagus+racemosus/" target="_blank">Asparagus racemosus</a>, <a href="http://examine.com/supplements/Choline/" target="_blank">Choline</a>, <a href="http://examine.com/supplements/Inositol/" target="_blank">Inositol</a>, <a href="http://examine.com/supplements/L-Tyrosine/" target="_blank">L-Tyrosine</a> and minerals) noted that pairing 400mg 7-Keto (200mg twice daily) with a calorically restricted diet (25kcal/kg of target body weight) and exercise program for 8 weeks noted similar effects (increasing weight loss from 0.72+/-2.12kg in placebo to 2.15+/-2.38kg; high variability seemed to be due to exercise/diet intervention rather than supplementation as it occurred in placebo).<a href="http://examine.com/supplements/7-Keto+DHEA/#ref1" target="_blank">[1]</a></p><p>One study using 7-keto at 200mg (alongside <a href="http://examine.com/supplements/Green+Tea+Catechins/" target="_blank">Green Tea Catechins</a>, chromium, <a href="http://examine.com/supplements/Vitamin+D/" target="_blank">Vitamin D</a>, <a href="http://examine.com/supplements/Vitamin+C/" target="_blank">Vitamin C</a> and calcium) during a period of caloric restriction in obese adults noted that the supplement was associated with a 3.4% increase in metabolic rate (59+/-118kcal) while placebo decreased 3.4%.<a href="http://examine.com/supplements/7-Keto+DHEA/#ref36" target="_blank">[36]</a> One study suggests a spike n 7.2% of the metabolic rate, but this study used a subactive dose of 7-Keto (17mg) paired with a variety of stimulatory compounds (<a href="http://examine.com/supplements/Yerba+mate/" target="_blank">Yerba mate</a> at 167mg, piper nigrum at 1.7mg, 50mg <a href="http://examine.com/supplements/Coleus+forskohlii/" target="_blank">Coleus forskohlii</a>, 100mg Citris Aurantium at 6% <a href="http://examine.com/supplements/Synephrine/" target="_blank">Synephrine</a>, and 233mg Guarana at 22% <a href="http://examine.com/supplements/Caffeine/" target="_blank">Caffeine</a>).<a href="http://examine.com/supplements/7-Keto+DHEA/#ref2" target="_blank">[2]</a></p></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 1095, member: 3"] It has some effect on fat loss but it does not seem that great. I doubt that the pain and cramping you experience are due to the supplement but I suggest you consult your physician. Are you working out? Cramping can also be caused by calcium or other mineral deficiencies. This is from examine.com One study using 7-Keto in isolation at 200mg (100mg twice a day for 7 days) noted that, during a period of caloric restriction (800kcal less than regular intake), metabolic rate increased an average of 1.4% (total caloric expenditure a highly variable 21+/-115kcal) while placebo experienced a decrease in metabolic rate by 3.9% relative to baseline; this study was too short in duration to assess changes in weight.[URL="http://examine.com/supplements/7-Keto+DHEA/#ref36"][36][/URL] In accessing the metabolic rate, 7-Keto supplementation appears to attenuate or reverse the decline in metabolic rate associated with caloric restriction Studies conducted over a longer period of time note that 200mg (100mg twice daily) for 8 weeks in obese adults in combination with a weight loss diet (1800kcal mixed diet) and exercise program (3 days weeks cross training) noted that the loss in weight associated with placebo (0.97kg) was increased (2.88kg) as well as the fat loss (from 0.57% to 1.8%); no significant differences in dietary intake were reported.[URL="http://examine.com/supplements/7-Keto+DHEA/#ref27"][27][/URL] Studies measuring weight loss associated with 7-keto note that supplementation results in more weight and fat loss over a period of time; both studies were paired with diet and exercise which may be prerequisites Another trial (external funding source and confounded with [URL="http://examine.com/supplements/Asparagus+racemosus/"]Asparagus racemosus[/URL], [URL="http://examine.com/supplements/Choline/"]Choline[/URL], [URL="http://examine.com/supplements/Inositol/"]Inositol[/URL], [URL="http://examine.com/supplements/L-Tyrosine/"]L-Tyrosine[/URL] and minerals) noted that pairing 400mg 7-Keto (200mg twice daily) with a calorically restricted diet (25kcal/kg of target body weight) and exercise program for 8 weeks noted similar effects (increasing weight loss from 0.72+/-2.12kg in placebo to 2.15+/-2.38kg; high variability seemed to be due to exercise/diet intervention rather than supplementation as it occurred in placebo).[URL="http://examine.com/supplements/7-Keto+DHEA/#ref1"][1][/URL] One study using 7-keto at 200mg (alongside [URL="http://examine.com/supplements/Green+Tea+Catechins/"]Green Tea Catechins[/URL], chromium, [URL="http://examine.com/supplements/Vitamin+D/"]Vitamin D[/URL], [URL="http://examine.com/supplements/Vitamin+C/"]Vitamin C[/URL] and calcium) during a period of caloric restriction in obese adults noted that the supplement was associated with a 3.4% increase in metabolic rate (59+/-118kcal) while placebo decreased 3.4%.[URL="http://examine.com/supplements/7-Keto+DHEA/#ref36"][36][/URL] One study suggests a spike n 7.2% of the metabolic rate, but this study used a subactive dose of 7-Keto (17mg) paired with a variety of stimulatory compounds ([URL="http://examine.com/supplements/Yerba+mate/"]Yerba mate[/URL] at 167mg, piper nigrum at 1.7mg, 50mg [URL="http://examine.com/supplements/Coleus+forskohlii/"]Coleus forskohlii[/URL], 100mg Citris Aurantium at 6% [URL="http://examine.com/supplements/Synephrine/"]Synephrine[/URL], and 233mg Guarana at 22% [URL="http://examine.com/supplements/Caffeine/"]Caffeine[/URL]).[URL="http://examine.com/supplements/7-Keto+DHEA/#ref2"][2][/URL] [/QUOTE]
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DHEA Supplements- Do They Work?
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