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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
Determining optimal Free T value
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<blockquote data-quote="xqfq" data-source="post: 153848" data-attributes="member: 38167"><p>While this Tru-T method may be more accurate than previous calculated methods for the majority of people, it's still a proxy model and may not reflect reality. For instance, I've learned that SHBG <-> androgen binding affinity can differ between individuals, e.g. some people could have more or less "sticky" SHBG than others.</p><p></p><p>An example that may drive this home: magnesium changes the binding affinity of T to SHBG-- <a href="https://www.ncbi.nlm.nih.gov/pubmed/19095394" target="_blank">Magnesium effect on testosterone-SHBG association studied by a novel molecular chromatography approach. - PubMed - NCBI</a>. This is complicated stuff!</p></blockquote><p></p>
[QUOTE="xqfq, post: 153848, member: 38167"] While this Tru-T method may be more accurate than previous calculated methods for the majority of people, it's still a proxy model and may not reflect reality. For instance, I've learned that SHBG <-> androgen binding affinity can differ between individuals, e.g. some people could have more or less "sticky" SHBG than others. An example that may drive this home: magnesium changes the binding affinity of T to SHBG-- [URL="https://www.ncbi.nlm.nih.gov/pubmed/19095394"]Magnesium effect on testosterone-SHBG association studied by a novel molecular chromatography approach. - PubMed - NCBI[/URL]. This is complicated stuff! [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
Determining optimal Free T value
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