ExcelMale
Menu
Home
What's new
Latest activity
Forums
New posts
Search forums
What's new
New posts
Latest activity
Videos
Lab Tests
Doctor Finder
Buy Books
About Us
Men’s Health Coaching
Log in
Register
What's new
Search
Search
Search titles only
By:
New posts
Search forums
Menu
Log in
Register
Navigation
Install the app
Install
More options
Contact us
Close Menu
Forums
Expert Interviews
Questions for Specific Doctors & Experts
Desperate for advice on severe prostate issues due to hormone misuse
JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding.
You are using an out of date browser. It may not display this or other websites correctly.
You should upgrade or use an
alternative browser
.
Reply to thread
Message
<blockquote data-quote="Blackout" data-source="post: 117517" data-attributes="member: 18956"><p>I began experimenting on August 1st last year. I started using estradiol patches at the lowest dose combined with one proviron pill per day. The proviron was expensive for me, so I wasn't able to increase it, moreover, the main goal was the estradiol, not the DHT. I had no access to the full experiment report, but the important substance there was estradiol, not DHT.</p><p></p><p></p><p>Two weeks on that regime, I stopped proviron but continued with E2 patches and did tests. To my surprise, estradiol was 38 pg/ml, which is basically my own normal level -which was always a bit high, I know, but that was my level even prior to my first proviron use and that slightly elevated value explains why I have had slight gyno since a teenager and why I had always been so emotional before PSSD, because my E2 was always quite high. Highly emotional as a woman, that was me until 2010, and I miss that a lot. In fact back then I told myself that I had a predominant female brain, despite my 100% heterosexual but repressed being. Now I know the reason. Many girls during my youth referred to my extreme sensitivity which together with my sex drive, I miss a lot.</p><p></p><p>Since estradiol from the patch was so 'low' for my purposes, I desperately augmented the dose 4x, and added HCG. Two weeks like that, then another two weeks, adding sustanon 250 weekly. But I didn't do any more tests during that time to check what my levels were.</p><p></p><p>While my brain fog from years began lifting while doing that -with no other benefit-, at six weeks I began having unbearable pain in my armpits. Ultrasounds showed that they were enlarged lymph nodes, but apparently no mammary growth aside from my old and very mild gyno. That was rare. I always read estradiol causing gyno, not lymph node inflammation. It scared me a lot since research on armpit lymph node inflammation always mentioned cancer -and with E2 manipulation it seemed more obvious that it was not an infection-, so I stopped at the end of the sixth week while starting tamoxifen. By the way, when I tested my hormones just after quitting and before starting Nolva, my E2 was back to my normal, around 35, but free T was 17. Not an abnormal value, but I want to point out that it was a change for me, since during previous T trials since my crash from sertraline, my free T never took off from the very bottom of range -around 4- or even below despite my low SHBG. Although the general consensus is that high E2 decreases free T, when I did the estradiol trial the opposite occured to me.</p><p></p><p>Although my lymph nodes gradually became better, there were occasional, recurrent bouts of knife cutting pain not in the armpits but in my chest/breasts, more on the left one. I preferred to wait and wait but was determined to repeat and be more careful and observant.</p><p></p><p>Meanwhile, around December, I began having pelvic floor pain, for the first time in my life. I didn't know why, and didn't research since my obsession and fear was concentrated on the breast cancer risk. Additionally, just a year earlier -well before my estradiol trial-, I had LUTS issues although there was no pain that I could remember, just a persistent need to pee and incontinence all day long, not at night.</p><p></p><p>The pelvic floor pain went away after some weeks or a couple of months. During that time I had a pair of respiratory infections for which I had to take antibiotics. Don't know if that helped to ameliorate the pain.</p><p></p><p>By March 15, with no more armpit or pelvic floor pain, I began a second trial. But this time I didn't use exogenous estradiol. I simply decided to use 200 mg of T per week in divided doses and allow it to aromatize freely. This decision was made thinking about the fact that back in February 2012, when I still didn't know about PSSD but believed that my problem was due to residual hypogonadism from my proviron misuse in late 2010, I did my first T cycle -although very weak, almost the same dose used this time which is high TRT or very low cycle, just that I injected weekly that time. During that 2012 cycle, I wasn't feeling any better, until about 2 or 3 weeks on it, one single night I woke up completely reseted, with a raging erection and skyrocketed libido, with the obvious urge to find someone to let it be. However, I went back to sleep, and by next morning, it vanished, and did forever. That was the last time in my life -February 2012, one single night- when I ever experienced libido and felt connected to my emotions after being unemotional for a whole year while on sertraline and after it.</p><p></p><p>And I guess I know why it happened. Again, back in February 2012, I almost immediately found that I was having very swollen ankles and without teste, researching found that it was caused by high E2. So I introduced arimidex. And for the next years, every time I tried T, I used arimidex again -under the wrong, plain Bro-science idea that E2 is bad and only bad for men-, and I even used it alone with HCG for a long year in 2015 and early 2016, only to discover very late that I was an overresponder to anastrozole and that I probably lived with a crashed E2 again for over a year.</p><p></p><p>During my reasearch on the E2 as a possible treatment to reverse SSRI side effects, it was then that I learned how bad for the brain is the lack of estradiol, either if you are male or female, and that in turn helped me to deduce that before sertraline, my HPTA crash due to proviron initiated my mental deterioration, and I worsened a lot by using arimidex -in what were supposed to be very low doses twice weekly- specially in 2015, which left me with severe loss of short term memory and brain fog. And as I said, the brain fog lifted while I used estradiol, and my memory although still overall bad, was a bit better, which further made my interest in estradiol grow.</p><p></p><p>Well, I began experimenting again on March 15, and over the next few weeks I started to have nocturnal erections for the first time in 8 years. Daily. I can't describe how improved I felt just by being aware during midnight that I have a full erection, every night as it should have always been. And also some random mental partial erections during the day, which were totally absent too during those 8 years. Also I began thinking about women, not sexually, but I was having interest in them for sure and fantasizing that I will get even better and for the first time would be able to live at 35 years. How far from reality since I wasn't aware I was entering an even bigger problem.</p><p></p><p></p><p>I went to do tests. My E2 was at 91 (range 11-44), my TT was at 9.4 (range 1.75-7.8), but what I didn't expect at all was to find my free T being 101.1 (range 4.45-42). I expected my E2 to be that high, but not my free T, since as I said before, my free T never responded to T injections and it was always between 3.9 and 5.3, and only when I did the estradiol patches trial it went up to about 17. But I never, never expected it to skyrocket that way and in just a month, with a T dose that barely reached a minimal cycle. It is as if estradiol managed to unlock something that was locked, or turned it on by some means. And high free T equals to high DHT, although I didn't measure it. That scared me again, and immediately found that my HDL had plummeted and my hematocrit was on the upper limit. But that was not the worse part. By the way, my armpit lymph nodes were swollen and painful again.</p><p></p><p>I began to taper and also introduced arimidex again, at minimal, really minimal doses, just a scratch of the pill. I did weekly tests to check. My T gradually came down, but my E2 became a rollercoaster since definitely I'm an overresponder among overresponders to arimidex. One day it was 3, others it was 19, 55 and 47, so for me it is extremely difficult to aim for a given level using anastrozole.</p><p></p><p>However, on the first week of May I fell severely ill due to a new gastrointestinal infection, but it was so savage that I had to do two antibiotic rounds one after another and even then I remained with severe colitis and nausea for the next several weeks. And due to that problem I decided to taper more quickly, down to a dose that more or less yielded my own suboptimal levels.</p><p></p><p>But it was too late. As my gastrointestinal issues began fading, I noticed that the pelvic pain returned with a vengeance, and steadily rising in intensity, duration -all day- and type and location of pain, varing from dull to burning to pressure and discomfort, and currently it is more inside than in the perineum region. And I also began to go to pee at night from 2 to 4 times.</p><p></p><p>And what I found researching left me scared to death, more than when I was worried due to the armpit lymph nodes last year. As I told you, I was prepared to deal with breast issues and was aware too of the thrombosis risk -for which I was taking baby aspirin daily during my experiment-. But what I didn't know at all was that E2 has a lot of adverse effects on the prostate , but worse of that, not E2 alone but E2 + T, I found to be lethal, so to speak, 100% carcinogenic in rat experiments. The reports literally said that "combined E2 + T therapy gave rise to prostate cancer in 100% of treated rats". And not only that, but the fact that by 13 weeks, all of them had prostatitis and precancerous lesions, and by 36 weeks all of them had full blown cancer. My combined trial from last year and this one was about 22 weeks of messing with my prostate, although not all the time I had high E2 and/or high T, as for example my first weeks last year, my E2 with the low dose patch was almost my own, but I fear a lot the combined effects especially after my free T -and my DHT I guess- surged the way it did in March and April.</p><p></p><p>Continue…</p></blockquote><p></p>
[QUOTE="Blackout, post: 117517, member: 18956"] I began experimenting on August 1st last year. I started using estradiol patches at the lowest dose combined with one proviron pill per day. The proviron was expensive for me, so I wasn't able to increase it, moreover, the main goal was the estradiol, not the DHT. I had no access to the full experiment report, but the important substance there was estradiol, not DHT. Two weeks on that regime, I stopped proviron but continued with E2 patches and did tests. To my surprise, estradiol was 38 pg/ml, which is basically my own normal level -which was always a bit high, I know, but that was my level even prior to my first proviron use and that slightly elevated value explains why I have had slight gyno since a teenager and why I had always been so emotional before PSSD, because my E2 was always quite high. Highly emotional as a woman, that was me until 2010, and I miss that a lot. In fact back then I told myself that I had a predominant female brain, despite my 100% heterosexual but repressed being. Now I know the reason. Many girls during my youth referred to my extreme sensitivity which together with my sex drive, I miss a lot. Since estradiol from the patch was so 'low' for my purposes, I desperately augmented the dose 4x, and added HCG. Two weeks like that, then another two weeks, adding sustanon 250 weekly. But I didn't do any more tests during that time to check what my levels were. While my brain fog from years began lifting while doing that -with no other benefit-, at six weeks I began having unbearable pain in my armpits. Ultrasounds showed that they were enlarged lymph nodes, but apparently no mammary growth aside from my old and very mild gyno. That was rare. I always read estradiol causing gyno, not lymph node inflammation. It scared me a lot since research on armpit lymph node inflammation always mentioned cancer -and with E2 manipulation it seemed more obvious that it was not an infection-, so I stopped at the end of the sixth week while starting tamoxifen. By the way, when I tested my hormones just after quitting and before starting Nolva, my E2 was back to my normal, around 35, but free T was 17. Not an abnormal value, but I want to point out that it was a change for me, since during previous T trials since my crash from sertraline, my free T never took off from the very bottom of range -around 4- or even below despite my low SHBG. Although the general consensus is that high E2 decreases free T, when I did the estradiol trial the opposite occured to me. Although my lymph nodes gradually became better, there were occasional, recurrent bouts of knife cutting pain not in the armpits but in my chest/breasts, more on the left one. I preferred to wait and wait but was determined to repeat and be more careful and observant. Meanwhile, around December, I began having pelvic floor pain, for the first time in my life. I didn't know why, and didn't research since my obsession and fear was concentrated on the breast cancer risk. Additionally, just a year earlier -well before my estradiol trial-, I had LUTS issues although there was no pain that I could remember, just a persistent need to pee and incontinence all day long, not at night. The pelvic floor pain went away after some weeks or a couple of months. During that time I had a pair of respiratory infections for which I had to take antibiotics. Don't know if that helped to ameliorate the pain. By March 15, with no more armpit or pelvic floor pain, I began a second trial. But this time I didn't use exogenous estradiol. I simply decided to use 200 mg of T per week in divided doses and allow it to aromatize freely. This decision was made thinking about the fact that back in February 2012, when I still didn't know about PSSD but believed that my problem was due to residual hypogonadism from my proviron misuse in late 2010, I did my first T cycle -although very weak, almost the same dose used this time which is high TRT or very low cycle, just that I injected weekly that time. During that 2012 cycle, I wasn't feeling any better, until about 2 or 3 weeks on it, one single night I woke up completely reseted, with a raging erection and skyrocketed libido, with the obvious urge to find someone to let it be. However, I went back to sleep, and by next morning, it vanished, and did forever. That was the last time in my life -February 2012, one single night- when I ever experienced libido and felt connected to my emotions after being unemotional for a whole year while on sertraline and after it. And I guess I know why it happened. Again, back in February 2012, I almost immediately found that I was having very swollen ankles and without teste, researching found that it was caused by high E2. So I introduced arimidex. And for the next years, every time I tried T, I used arimidex again -under the wrong, plain Bro-science idea that E2 is bad and only bad for men-, and I even used it alone with HCG for a long year in 2015 and early 2016, only to discover very late that I was an overresponder to anastrozole and that I probably lived with a crashed E2 again for over a year. During my reasearch on the E2 as a possible treatment to reverse SSRI side effects, it was then that I learned how bad for the brain is the lack of estradiol, either if you are male or female, and that in turn helped me to deduce that before sertraline, my HPTA crash due to proviron initiated my mental deterioration, and I worsened a lot by using arimidex -in what were supposed to be very low doses twice weekly- specially in 2015, which left me with severe loss of short term memory and brain fog. And as I said, the brain fog lifted while I used estradiol, and my memory although still overall bad, was a bit better, which further made my interest in estradiol grow. Well, I began experimenting again on March 15, and over the next few weeks I started to have nocturnal erections for the first time in 8 years. Daily. I can't describe how improved I felt just by being aware during midnight that I have a full erection, every night as it should have always been. And also some random mental partial erections during the day, which were totally absent too during those 8 years. Also I began thinking about women, not sexually, but I was having interest in them for sure and fantasizing that I will get even better and for the first time would be able to live at 35 years. How far from reality since I wasn't aware I was entering an even bigger problem. I went to do tests. My E2 was at 91 (range 11-44), my TT was at 9.4 (range 1.75-7.8), but what I didn't expect at all was to find my free T being 101.1 (range 4.45-42). I expected my E2 to be that high, but not my free T, since as I said before, my free T never responded to T injections and it was always between 3.9 and 5.3, and only when I did the estradiol patches trial it went up to about 17. But I never, never expected it to skyrocket that way and in just a month, with a T dose that barely reached a minimal cycle. It is as if estradiol managed to unlock something that was locked, or turned it on by some means. And high free T equals to high DHT, although I didn't measure it. That scared me again, and immediately found that my HDL had plummeted and my hematocrit was on the upper limit. But that was not the worse part. By the way, my armpit lymph nodes were swollen and painful again. I began to taper and also introduced arimidex again, at minimal, really minimal doses, just a scratch of the pill. I did weekly tests to check. My T gradually came down, but my E2 became a rollercoaster since definitely I'm an overresponder among overresponders to arimidex. One day it was 3, others it was 19, 55 and 47, so for me it is extremely difficult to aim for a given level using anastrozole. However, on the first week of May I fell severely ill due to a new gastrointestinal infection, but it was so savage that I had to do two antibiotic rounds one after another and even then I remained with severe colitis and nausea for the next several weeks. And due to that problem I decided to taper more quickly, down to a dose that more or less yielded my own suboptimal levels. But it was too late. As my gastrointestinal issues began fading, I noticed that the pelvic pain returned with a vengeance, and steadily rising in intensity, duration -all day- and type and location of pain, varing from dull to burning to pressure and discomfort, and currently it is more inside than in the perineum region. And I also began to go to pee at night from 2 to 4 times. And what I found researching left me scared to death, more than when I was worried due to the armpit lymph nodes last year. As I told you, I was prepared to deal with breast issues and was aware too of the thrombosis risk -for which I was taking baby aspirin daily during my experiment-. But what I didn't know at all was that E2 has a lot of adverse effects on the prostate , but worse of that, not E2 alone but E2 + T, I found to be lethal, so to speak, 100% carcinogenic in rat experiments. The reports literally said that "combined E2 + T therapy gave rise to prostate cancer in 100% of treated rats". And not only that, but the fact that by 13 weeks, all of them had prostatitis and precancerous lesions, and by 36 weeks all of them had full blown cancer. My combined trial from last year and this one was about 22 weeks of messing with my prostate, although not all the time I had high E2 and/or high T, as for example my first weeks last year, my E2 with the low dose patch was almost my own, but I fear a lot the combined effects especially after my free T -and my DHT I guess- surged the way it did in March and April. Continue… [/QUOTE]
Insert quotes…
Verification
Post reply
Share this page
Facebook
Twitter
Reddit
Pinterest
Tumblr
WhatsApp
Email
Share
Link
Sponsors
Forums
Expert Interviews
Questions for Specific Doctors & Experts
Desperate for advice on severe prostate issues due to hormone misuse
This site uses cookies to help personalise content, tailor your experience and to keep you logged in if you register.
By continuing to use this site, you are consenting to our use of cookies.
Accept
Learn more…
Top