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<blockquote data-quote="Kenny Croxdale" data-source="post: 220137" data-attributes="member: 43368"><p><h3>Ketones as Treatment for Alzheimers</h3><p>This is a great presentation by Dr Mary Newport.</p><p></p><p><strong>Type III Diabetes</strong></p><p></p><p>Alzheimers is now being labeled as Type III Diabetes.</p><p></p><p>One of the issues with Alzheimers is that the brain becomes unable to utilize glucose to essentially "Turn on the lights" and allow the brain to function.</p><p></p><p>The brain ends up starving because it is unable to utilize glucose to feed it.</p><p></p><p>Research shows, as Newport goes into, that the brain is able to utilize ketones to "Turn the lights on" and nourish it to some degree.</p><p></p><p>Thus, individuals with Alzheimers or cognitive disorders are able to function somewhat better.</p><p></p><p><strong>Traumatic Brain Injury, TBI</strong></p><p></p><p>Individuals who suffer from concussions also cannot utilize glucose effectively in the brain.</p><p></p><p>However, with TBI individuals are able to utilize ketones to run the brain.</p><p></p><p><strong>"The Brain Is A Glucose Hog"</strong></p><p></p><p>Normal individuals on a high carbohydrate diet require a lot of glucose to run the brain.</p><p></p><p>Research indicates that between 100-150 gram of glucose per day is needed for the brain to function.</p><p></p><p>However, all that changes when individuals...</p><p></p><p><strong>Shifting To The Ketogenic Diet</strong></p><p></p><p>Once "Keto Adapted" the brain primarily used ketones as fuel.</p><p></p><p>While the brain still needS some glucose. the amount of glucose needed on a Ketogenic Diet dropS down to 20%. 80% of the brains function driven by ketones.</p><p></p><p>That means rather than needing 100-150 gram of glucose per day, the brain works efficiently with around 20-30 gram a day.</p><p></p><p>That amount of glucose on a low carbohydrate diet is provide by the 50 gram or less of carbohydrates consumed, as well as...</p><p></p><p><strong>Gluconeogenesis</strong></p><p></p><p>This means the body breaks down some protein and triglycerides, converting them to glucose.</p><p></p><p><strong>The Ketogenic Diet Is NOT Catabolic</strong></p><p></p><p>Many individuals believe the Ketogenic Diet is catabolic, muscle being broken down into glucose; which isn't true on a well formulated Keto Diet.</p><p></p><p>Research shows that on a Keto Diet, ketones are preferred and the primary source of fuel; sparing glucose.</p><p></p><p>An indiviual who is "Keto Adapted '' is shown to have essentially the same amount of glucose as an individual on a high carbohydrate diet.</p><p></p><p>The caveat is that The Ketogenic Diet has converted the body's machinery to utilizing ketones, it is more effective at using ketone and does not access glycogen as efficiently.</p><p></p><p>Previous information on "How To Train On A Ketogenic Diet" has been posted on this site.</p><p></p><p>Secondly, the body becomes more efficient at utilizing ketone and sparing protein and muscle.</p><p></p><p>Research shows that Fasting up to 72 hours (Ketone State) primarily uses ketones, preserving muscle mass.</p><p></p><p>Third, research (Volek/Phinney) found higher Leucine levels in "Keto Adpated" individual. Leucine is the anabolic amino acid that maintains or increases muscle mass.</p><p></p><p><strong>Preservation</strong></p><p></p><p>The reason that the body primarily utilizes body fat (ketones), preserving muscle mass and increasing Leucine blood levels in Fasting or on a Ketogenic Diet is because the body autoregulates. It goes into survival mode.</p><p></p><p>It realizes that muscle mass is necessary for survival and body fat/ketones are expendable.</p><p></p><p>Add to that, let's say a 150 lb person is 15% body fat. That means they have 22.5 lb of body fat,</p><p></p><p>That mean they have 78,750 stored calories. (22.5 lbs body fat X 3500 calories per pound).</p><p></p><p>Now let's move to...</p><p></p><p><strong>Feeding An Alzheimers Brain</strong></p><p></p><p>These individuals need more ketones.</p><p></p><p>They can still consume a fairly high carbohydrate diet.</p><p></p><p>However, to obtain more ketones, they need to consume more fat...especially Coconut Oil and/or Medium Chain Trlglycridesm, MCT Oil.</p><p></p><p>As per Newport...</p><p></p><p><strong>How Much Coconut Oil for Alzheimer's & Dementia?</strong>[MEDIA=youtube]I3UfgQ9vkr0[/MEDIA]</p><p></p><p><strong>1) Coconut Oil</strong></p><p>2:50 minute mark</p><p></p><p>a) Ketone level peaks at about 3 hour after taking Coconut Oil.</p><p></p><p>b) Ketones remained in the system for 7 - 8 hours.</p><p></p><p><strong>2) MCT Oil</strong></p><p>3:00 minutes mark</p><p></p><p>a) Ketone level is higher but peaked at 90 minutes.</p><p></p><p>b) Ketones gone at 3 hours</p><p></p><p>Based on this information, it appears that a combination of Coconut Oil and MCT Oil would be most effective.</p><p></p><p>Coconut Oil provides a "Time Released" effect of ketones.</p><p></p><p>MCT Oil provides "Faster Released" ketones.</p></blockquote><p></p>
[QUOTE="Kenny Croxdale, post: 220137, member: 43368"] [HEADING=2]Ketones as Treatment for Alzheimers[/HEADING] This is a great presentation by Dr Mary Newport. [B]Type III Diabetes[/B] Alzheimers is now being labeled as Type III Diabetes. One of the issues with Alzheimers is that the brain becomes unable to utilize glucose to essentially "Turn on the lights" and allow the brain to function. The brain ends up starving because it is unable to utilize glucose to feed it. Research shows, as Newport goes into, that the brain is able to utilize ketones to "Turn the lights on" and nourish it to some degree. Thus, individuals with Alzheimers or cognitive disorders are able to function somewhat better. [B]Traumatic Brain Injury, TBI[/B] Individuals who suffer from concussions also cannot utilize glucose effectively in the brain. However, with TBI individuals are able to utilize ketones to run the brain. [B]"The Brain Is A Glucose Hog"[/B] Normal individuals on a high carbohydrate diet require a lot of glucose to run the brain. Research indicates that between 100-150 gram of glucose per day is needed for the brain to function. However, all that changes when individuals... [B]Shifting To The Ketogenic Diet[/B] Once "Keto Adapted" the brain primarily used ketones as fuel. While the brain still needS some glucose. the amount of glucose needed on a Ketogenic Diet dropS down to 20%. 80% of the brains function driven by ketones. That means rather than needing 100-150 gram of glucose per day, the brain works efficiently with around 20-30 gram a day. That amount of glucose on a low carbohydrate diet is provide by the 50 gram or less of carbohydrates consumed, as well as... [B]Gluconeogenesis[/B] This means the body breaks down some protein and triglycerides, converting them to glucose. [B]The Ketogenic Diet Is NOT Catabolic[/B] Many individuals believe the Ketogenic Diet is catabolic, muscle being broken down into glucose; which isn't true on a well formulated Keto Diet. Research shows that on a Keto Diet, ketones are preferred and the primary source of fuel; sparing glucose. An indiviual who is "Keto Adapted '' is shown to have essentially the same amount of glucose as an individual on a high carbohydrate diet. The caveat is that The Ketogenic Diet has converted the body's machinery to utilizing ketones, it is more effective at using ketone and does not access glycogen as efficiently. Previous information on "How To Train On A Ketogenic Diet" has been posted on this site. Secondly, the body becomes more efficient at utilizing ketone and sparing protein and muscle. Research shows that Fasting up to 72 hours (Ketone State) primarily uses ketones, preserving muscle mass. Third, research (Volek/Phinney) found higher Leucine levels in "Keto Adpated" individual. Leucine is the anabolic amino acid that maintains or increases muscle mass. [B]Preservation[/B] The reason that the body primarily utilizes body fat (ketones), preserving muscle mass and increasing Leucine blood levels in Fasting or on a Ketogenic Diet is because the body autoregulates. It goes into survival mode. It realizes that muscle mass is necessary for survival and body fat/ketones are expendable. Add to that, let's say a 150 lb person is 15% body fat. That means they have 22.5 lb of body fat, That mean they have 78,750 stored calories. (22.5 lbs body fat X 3500 calories per pound). Now let's move to... [B]Feeding An Alzheimers Brain[/B] These individuals need more ketones. They can still consume a fairly high carbohydrate diet. However, to obtain more ketones, they need to consume more fat...especially Coconut Oil and/or Medium Chain Trlglycridesm, MCT Oil. As per Newport... [B]How Much Coconut Oil for Alzheimer's & Dementia?[/B][MEDIA=youtube]I3UfgQ9vkr0[/MEDIA] [B]1) Coconut Oil[/B] 2:50 minute mark a) Ketone level peaks at about 3 hour after taking Coconut Oil. b) Ketones remained in the system for 7 - 8 hours. [B]2) MCT Oil[/B] 3:00 minutes mark a) Ketone level is higher but peaked at 90 minutes. b) Ketones gone at 3 hours Based on this information, it appears that a combination of Coconut Oil and MCT Oil would be most effective. Coconut Oil provides a "Time Released" effect of ketones. MCT Oil provides "Faster Released" ketones. [/QUOTE]
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