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So have all of my ducks in a row to get started with Defy. I'm SUPER excited to finally get expert help with the, so far, disappointing journey of TRT. On that note, any opinions on which doc I should consult with? I've read about a hundred good things about both Dr Saya and Dr Crisler, so I'm sure I probably won't go wrong either way. I've watched many videos of both and I get the slight feel that Dr Saya may be more of a personality match for me. Just curious if any guys have any pearls of wisdom to consider about either doctors' communication, openness, answering (sometimes dumb) questions, etc. or any other details to consider. Thanks!


P.S. It seems Dr Saya is booked out a couple more weeks than Dr Crisler, but that really doesn't matter to me if he would be the right choice for me personally in the long run. Excited to get started.


TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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