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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Decreasing High Hematocrit: Genistein is an agonist of hepcidin
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<blockquote data-quote="Tron" data-source="post: 113017" data-attributes="member: 12371"><p>Hello:</p><p></p><p>Hematocrit increase is a very known side of TRT. Some studies conclude that testosterone reduces hepcidin (an hepatic hormone) which is related with iron absorptions paths. When hepcidin is reduced erythrocytosis is increased:</p><p></p><p><a href="https://www.ncbi.nlm.nih.gov/pubmed/20660052" target="_blank">Testosterone suppresses hepcidin in men: a potential mechanism for testosterone-induced erythrocytosis - PubMed</a></p><p></p><p>There is some hepcidin agonists. One of the is called genistein:</p><p></p><p><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998755/" target="_blank">Hepcidin: A Promising Therapeutic Target for Iron Disorders</a></p><p></p><p>"Through high-throughput screening, several compounds including genistein and progesterone are identified because they show excellent efficacy in hepcidin induction.56,90"</p><p></p><p>This is another info about genistein:</p><p></p><p><a href="https://en.wikipedia.org/wiki/Genistein" target="_blank">Genistein - Wikipedia</a></p><p></p><p>"Isoflavones such as genistein and daidzein are found in a number of plants including lupin, fava beans, soybeans, kudzu, and psoralea being the primary food source,[2][3] also in the medicinal plants, Flemingia vestita[4] and F. macrophylla,[5][6] and coffee.[7] It can also be found in Maackia amurensis cell cultures.[8]"</p><p></p><p>Of course, we can buy genistein in some comercial stores because it is not too much difficult to extract form these foods.</p><p></p><p>Any ideas about genistein???</p><p></p><p>Thanks</p></blockquote><p></p>
[QUOTE="Tron, post: 113017, member: 12371"] Hello: Hematocrit increase is a very known side of TRT. Some studies conclude that testosterone reduces hepcidin (an hepatic hormone) which is related with iron absorptions paths. When hepcidin is reduced erythrocytosis is increased: [URL="https://www.ncbi.nlm.nih.gov/pubmed/20660052"]Testosterone suppresses hepcidin in men: a potential mechanism for testosterone-induced erythrocytosis - PubMed[/URL] There is some hepcidin agonists. One of the is called genistein: [URL="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998755/"]Hepcidin: A Promising Therapeutic Target for Iron Disorders[/URL] "Through high-throughput screening, several compounds including genistein and progesterone are identified because they show excellent efficacy in hepcidin induction.56,90" This is another info about genistein: [URL="https://en.wikipedia.org/wiki/Genistein"]Genistein - Wikipedia[/URL] "Isoflavones such as genistein and daidzein are found in a number of plants including lupin, fava beans, soybeans, kudzu, and psoralea being the primary food source,[2][3] also in the medicinal plants, Flemingia vestita[4] and F. macrophylla,[5][6] and coffee.[7] It can also be found in Maackia amurensis cell cultures.[8]" Of course, we can buy genistein in some comercial stores because it is not too much difficult to extract form these foods. Any ideas about genistein??? Thanks [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Decreasing High Hematocrit: Genistein is an agonist of hepcidin
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