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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Daily Intramuscular injections.
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<blockquote data-quote="Anonymon" data-source="post: 207344" data-attributes="member: 42608"><p>This thread’s a good example of how everyone needs to find what works for them and take all the ‘studies’ in the world with a grain of salt. Nothing can compare to your own experience, provided you give it time and evaluate it carefully.</p><p></p><p>This all reminds me of thyroid meds. Some people do great on T4. Some people do great on T3. Some people do great with both, or NDT. Everybody’s different. They’re all theoretically interchangeable and practically not at all interchangeable for many.</p><p></p><p>The differences in how people feel based on the injection method probably have nothing to do with how it affects your TT or FT in the same way that taking something like pregnenolone in a pill vs transdermal can effect people wildly differently. In that case you can say skin has a lot of 5AR in it and there’s a theoretical mechanism, but just because we don’t know what might be different when injecting in the muscle vs skin doesn’t mean the endless anecdotes of some guys doing better on one method vs the other are them blowing smoke out their ass. You’d think it’d all be the same since it has to go through the liver to metabolize, but we find out new things about all this every day. Us sticking ourselves in the ass and talking about it’s the forefront of HRT, not a lab.</p><p></p><p>Although I inject subQ and have never tried otherwise, I know more guys that actually say they felt better on IM. And I have no reason not to believe them because of something I found on PubMed. If you do fine on SubQ I think it’d be superior for ease of injection and lack of scarring, but I do believe all the people saying IM works better for them. It’s kind of weird if you think about it to tell a bunch of folks what’s working for them isn’t working for them for reasons unknown. It’s gaslighting at a certain point. I get that if one guy shows up blowing out nonsense you scrutinize it, but it’s not one guy. A lot of guys feel better on IM. To what end should we gaslight them? Because we prefer SubQ?</p><p></p><p>IM vs SubQ is just another lever someone can pull when trying HRT to make it work for them.</p></blockquote><p></p>
[QUOTE="Anonymon, post: 207344, member: 42608"] This thread’s a good example of how everyone needs to find what works for them and take all the ‘studies’ in the world with a grain of salt. Nothing can compare to your own experience, provided you give it time and evaluate it carefully. This all reminds me of thyroid meds. Some people do great on T4. Some people do great on T3. Some people do great with both, or NDT. Everybody’s different. They’re all theoretically interchangeable and practically not at all interchangeable for many. The differences in how people feel based on the injection method probably have nothing to do with how it affects your TT or FT in the same way that taking something like pregnenolone in a pill vs transdermal can effect people wildly differently. In that case you can say skin has a lot of 5AR in it and there’s a theoretical mechanism, but just because we don’t know what might be different when injecting in the muscle vs skin doesn’t mean the endless anecdotes of some guys doing better on one method vs the other are them blowing smoke out their ass. You’d think it’d all be the same since it has to go through the liver to metabolize, but we find out new things about all this every day. Us sticking ourselves in the ass and talking about it’s the forefront of HRT, not a lab. Although I inject subQ and have never tried otherwise, I know more guys that actually say they felt better on IM. And I have no reason not to believe them because of something I found on PubMed. If you do fine on SubQ I think it’d be superior for ease of injection and lack of scarring, but I do believe all the people saying IM works better for them. It’s kind of weird if you think about it to tell a bunch of folks what’s working for them isn’t working for them for reasons unknown. It’s gaslighting at a certain point. I get that if one guy shows up blowing out nonsense you scrutinize it, but it’s not one guy. A lot of guys feel better on IM. To what end should we gaslight them? Because we prefer SubQ? IM vs SubQ is just another lever someone can pull when trying HRT to make it work for them. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Daily Intramuscular injections.
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