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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Daily Intramuscular injections.
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<blockquote data-quote="Cataceous" data-source="post: 207195" data-attributes="member: 38109"><p>A rigorous scientific method is all the more important in evaluating subjective results; people easily fool themselves. Without blinded testing you often have biases obliterating reality.</p><p></p><p>Let's make it $100,000 so that you'll have enough of your spare million left to afford a proper study. I'm thinking N>=100 with outside administrators, maybe testosterone undecanoate injected a couple times a week to ensure steady serum testosterone levels. It'll be a blinded crossover study with three phases: a loading phase where the method of injection is unimportant, then a phase with simultaneous subcutaneous and intramuscular injections in which one is only the carrier and the other is the carrier with the testosterone, then a phase in which the medications are reversed. Unfortunately the long half-life of undecanoate means that each phase should be at least five months—but it limits the number of injections. Even if money were no object it's hard to imagine that you and your friends and the other volunteers rounding out the 100 would be able to manage supervised double injections daily. These would be needed for a shorter ester like testosterone cypionate. We'll evaluate the results two ways: serum testosterone measured between injections three times near the end of each phase; a subjective evaluation by each subject.</p><p></p><p>If IM exceeds SC by both measures in a statistically significant manner then you win. If IM doesn't exceed SC by either measure then I win. If they're split then it's a draw.</p><p></p><p></p><p>There is absolutely no credible evidence for this. It's foolish advice that should be ignored.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 207195, member: 38109"] A rigorous scientific method is all the more important in evaluating subjective results; people easily fool themselves. Without blinded testing you often have biases obliterating reality. Let's make it $100,000 so that you'll have enough of your spare million left to afford a proper study. I'm thinking N>=100 with outside administrators, maybe testosterone undecanoate injected a couple times a week to ensure steady serum testosterone levels. It'll be a blinded crossover study with three phases: a loading phase where the method of injection is unimportant, then a phase with simultaneous subcutaneous and intramuscular injections in which one is only the carrier and the other is the carrier with the testosterone, then a phase in which the medications are reversed. Unfortunately the long half-life of undecanoate means that each phase should be at least five months—but it limits the number of injections. Even if money were no object it's hard to imagine that you and your friends and the other volunteers rounding out the 100 would be able to manage supervised double injections daily. These would be needed for a shorter ester like testosterone cypionate. We'll evaluate the results two ways: serum testosterone measured between injections three times near the end of each phase; a subjective evaluation by each subject. If IM exceeds SC by both measures in a statistically significant manner then you win. If IM doesn't exceed SC by either measure then I win. If they're split then it's a draw. There is absolutely no credible evidence for this. It's foolish advice that should be ignored. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Daily Intramuscular injections.
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