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I agree that EOD should be enough but daily (in my mind) is easier to follow than EOD. I would have to set up reminders in my cell phone etc. Daily i know that i have to do it every single day. E3.5D for me would be ideal. But looks like with my SHBG levels it is not working great for me. I was thinking of maybe increasing the dosage and stay with 3.5D protocol. But it would probably create more E2 and HCT issues.

[QUOTE="HealthMan, post: 86450, member: 13512"] I agree that EOD should be enough but daily (in my mind) is easier to follow than EOD. I would have to set up reminders in my cell phone etc. Daily i know that i have to do it every single day. E3.5D for me would be ideal. But looks like with my SHBG levels it is not working great for me. I was thinking of maybe increasing the dosage and stay with 3.5D protocol. But it would probably create more E2 and HCT issues. [/QUOTE]