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I recently got a call from my TRT Dr (A) turning down my request for renewing Sildenafil, because he checked my "medication profile" and found that I was seeing a urologist (B) who prescribed daily 5 mg Cialis for me (mainly to fend off BPH).  The claim from A was that the two drugs have an adverse interaction when used together.  I checked this on drugs.com : 


Cialis and Viagra Drug Interactions - Drugs.com.


Not only does this reference state that there is no interaction between the two drugs, but that a Therapeutic Duplication benefit for treating ED might outweigh any risks.  I recall reading about this several times in this forum - Cialis doesn't quite bring you where you need to be (or has different reaction times in different men), so you top it off with Viagra (Sildnafil) closer to the time of activity.  Sildenafil typically acts faster and more reliably, especially in men who have lost sensitivity to Cialis.


It seems the medical profession has a way to go for multiple Mds to track a single patient's records.  Some of it is on me too.  I plan to cite the drugs.com reference to Dr A, give him Dr B's contact info, and if Dr A still won't give me the Sildenafil Rx, I'm sure Dr B will.  I just have to be tactful enough not to lose my rapport with Dr A, because TRT has been good for me.


TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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