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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
Creatine Phosphokinase (CPK) - Does Testosterone Impact It?
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<blockquote data-quote="GEORGE TOULIATOS" data-source="post: 80132" data-attributes="member: 12529"><p>In case of an elevated CPK,doctors also check out fragment CK-MB of myocardium.Usually,its elevated under AMI,along with troponin protein,ALT,AST,LDH.All these biochemical measurements are part of a damaged heart muscle.</p><p>Another case is rhabdomyolysis effect,under vigorous physical activity.Also numerous IM injections can damage skeletal muscle tissue and reflect on serum CPK.Finally cocaine abuse can lead to rhabdo as well.</p><p>You should know that as striated muscle is broken down,myoglobin protein responsible for O2 transport to contractile muscles, is released into plasma.Apparently that protein becomes toxic to renal glomerulus.</p><p>But rhabdo is officially when CPK is >10x its higher range.Therefore,when CPK>1,000 it evaluated as something to be concerned of.Today there was apatient in my office,who's CPK was>12,000!</p><p>As i excpected,one of his transaminases was elevated.This occurs,simply because both muscle-,liver and heart share common receptors for ALT/AST-SGPT/SGOT.</p><p>[ATTACH]4009[/ATTACH]</p></blockquote><p></p>
[QUOTE="GEORGE TOULIATOS, post: 80132, member: 12529"] In case of an elevated CPK,doctors also check out fragment CK-MB of myocardium.Usually,its elevated under AMI,along with troponin protein,ALT,AST,LDH.All these biochemical measurements are part of a damaged heart muscle. Another case is rhabdomyolysis effect,under vigorous physical activity.Also numerous IM injections can damage skeletal muscle tissue and reflect on serum CPK.Finally cocaine abuse can lead to rhabdo as well. You should know that as striated muscle is broken down,myoglobin protein responsible for O2 transport to contractile muscles, is released into plasma.Apparently that protein becomes toxic to renal glomerulus. But rhabdo is officially when CPK is >10x its higher range.Therefore,when CPK>1,000 it evaluated as something to be concerned of.Today there was apatient in my office,who's CPK was>12,000! As i excpected,one of his transaminases was elevated.This occurs,simply because both muscle-,liver and heart share common receptors for ALT/AST-SGPT/SGOT. [ATTACH=CONFIG]4009[/ATTACH] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
Creatine Phosphokinase (CPK) - Does Testosterone Impact It?
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