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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
couple Qs about T cream
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<blockquote data-quote="madman" data-source="post: 140491" data-attributes="member: 13851"><p>Steady state should be achieved 48-72 hrs.</p><p></p><p></p><p></p><p></p><p><strong>Pharmacokinetics of testosterone cream applied to scrotal skin </strong></p><p></p><p><strong><span style="color: rgb(184, 49, 47)">*R. Iyer, *S. F. Mok, S. Savkovic, L. Turner, G. Fraser, R. Desai, V. Jayadev, A. J. Conway and D. J. Handelsman </span></strong></p><p></p><p></p><p></p><p></p><p><strong>DISCUSSION </strong></p><p>This study provides a pharmacokinetic profile of three doses of testosterone administered to the scrotal skin in a cream formulation. <strong><span style="color: rgb(184, 49, 47)">Application of the testosterone cream produced a </span><span style="color: rgb(0, 0, 0)">rapid rise in serum testosterone peaking around</span> <span style="color: rgb(0, 0, 0)">2 h after administration </span></strong><span style="color: rgb(0, 0, 0)">with a dose-dependent peak concentration, but not any consistent relationship between time of peak and testosterone dose. </span><strong>At the lowest dose <span style="color: rgb(184, 49, 47)">(12.5 mg)</span>, the serum testosterone concentrations were maintained in physiological range for <span style="color: rgb(184, 49, 47)">at least 12 h </span>and with the <span style="color: rgb(184, 49, 47)">25 mg dose </span>maintained serum testosterone</strong> <strong>concentrations within the physiological range <span style="color: rgb(184, 49, 47)">for nearly 24 h concentration. </span></strong></p></blockquote><p></p>
[QUOTE="madman, post: 140491, member: 13851"] Steady state should be achieved 48-72 hrs. [B]Pharmacokinetics of testosterone cream applied to scrotal skin [/B] [B][COLOR=rgb(184, 49, 47)]*R. Iyer, *S. F. Mok, S. Savkovic, L. Turner, G. Fraser, R. Desai, V. Jayadev, A. J. Conway and D. J. Handelsman [/COLOR][/B] [B]DISCUSSION [/B] This study provides a pharmacokinetic profile of three doses of testosterone administered to the scrotal skin in a cream formulation. [B][COLOR=rgb(184, 49, 47)]Application of the testosterone cream produced a [/COLOR][COLOR=rgb(0, 0, 0)]rapid rise in serum testosterone peaking around[/COLOR][COLOR=rgb(184, 49, 47)] [/COLOR][COLOR=rgb(0, 0, 0)]2 h after administration [/COLOR][/B][COLOR=rgb(0, 0, 0)]with a dose-dependent peak concentration, but not any consistent relationship between time of peak and testosterone dose. [/COLOR][B]At the lowest dose [COLOR=rgb(184, 49, 47)](12.5 mg)[/COLOR], the serum testosterone concentrations were maintained in physiological range for [COLOR=rgb(184, 49, 47)]at least 12 h [/COLOR]and with the [COLOR=rgb(184, 49, 47)]25 mg dose [/COLOR]maintained serum testosterone[/B] [B]concentrations within the physiological range [COLOR=rgb(184, 49, 47)]for nearly 24 h concentration. [/COLOR][/B] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
couple Qs about T cream
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