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Message: <blockquote data-quote="Nelson Vergel" data-source="post: 153262" data-attributes="member: 3">xpfqThanks for the thought-provoking post.  A few guys here have used progesterone, so you may ask them if they experienced less water retention.<a href="https://www.google.com/search?biw=1795&bih=870&ei=MWMjXcboDMSM9PwPuoKGoAo&q=progesterone++excelmale.com+site%3Awww.excelmale.com&oq=progesterone++excelmale.com+site%3Awww.excelmale.com&gs_l=psy-ab.3...3194.3899..4677...0.0..0.347.1128.0j2j2j1......0....1..gws-wiz.afv3euq-gHE" target="_blank">progesterone  excelmale.com site:www.excelmale.com - Google Search</a> "Elevated levels of progesterone potently reduce the sodium-retaining activity of aldosterone, resulting in natriuresis and a reduction in extracellular fluid volume. Progesterone withdrawal, on the other hand, is associated with a temporary increase in sodium retention (reduced natriuresis, with an increase in extracellular fluid volume) due to the compensatory increase in aldosterone production, which combats the blockade of the mineralocorticoid receptor by the previously elevated level of progesterone." Reference attached.My gut feeling tells me that water retention on TRT, HCG or anabolic steroids has more to do with their effect on kidneys' sodium excretion. <a href="https://www.hindawi.com/journals/aps/2011/817835/" target="_blank">Testosterone Increases: Sodium Reabsorption, Blood Pressure, and Renal Pathology in Female Spontaneously Hypertensive Rats on a High Sodium Diet</a> <a href="https://academic.oup.com/jcem/article/90/7/3989/2837248" target="_blank">https://academic.oup.com/jcem/article/90/7/3989/2837248</a></blockquote>

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