ExcelMale
Menu
Home
What's new
Latest activity
Forums
New posts
Search forums
What's new
New posts
Latest activity
Videos
Lab Tests
Doctor Finder
Buy Books
About Us
Men’s Health Coaching
Log in
Register
What's new
Search
Search
Search titles only
By:
New posts
Search forums
Menu
Log in
Register
Navigation
Install the app
Install
More options
Contact us
Close Menu
Forums
General Health & Fitness
Health & Wellness
Coronavirus COVID-19 Update: Hydroxychloroquine and Other Treatments
JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding.
You are using an out of date browser. It may not display this or other websites correctly.
You should upgrade or use an
alternative browser
.
Reply to thread
Message
<blockquote data-quote="sammmy" data-source="post: 175302" data-attributes="member: 38594"><p>The in vitro effective concentration of Hydroxychloroquine sulphate (molar mass = 434 g/mol) against COVID-19 is cited as EC50 = 0.73 microM =</p><p>= 0.73 * 10^-6 mol/Liter = </p><p>= 0.73 * 10^-6 * 434 g /Liter = </p><p>= 3.17 * 10^-4 g/Liter = </p><p>= 3.17 * 10^-7 g/mL = </p><p>= 317 * 10^-9 g/mL =</p><p>= 317 ng/mL.</p><p></p><p>If the Plaquenil insert is correct, reaching the EC50 concentration will require 317/53 = 6 doses of 200mg Plaquenil pills. The French study uses 3 x 200mg pills each day so the EC50 will be reached at the end of the second day of dosing. That probably supports the idea that hydroxychloroquine has to be started EARLY not when the patient is already intubated and dying.</p></blockquote><p></p>
[QUOTE="sammmy, post: 175302, member: 38594"] The in vitro effective concentration of Hydroxychloroquine sulphate (molar mass = 434 g/mol) against COVID-19 is cited as EC50 = 0.73 microM = = 0.73 * 10^-6 mol/Liter = = 0.73 * 10^-6 * 434 g /Liter = = 3.17 * 10^-4 g/Liter = = 3.17 * 10^-7 g/mL = = 317 * 10^-9 g/mL = = 317 ng/mL. If the Plaquenil insert is correct, reaching the EC50 concentration will require 317/53 = 6 doses of 200mg Plaquenil pills. The French study uses 3 x 200mg pills each day so the EC50 will be reached at the end of the second day of dosing. That probably supports the idea that hydroxychloroquine has to be started EARLY not when the patient is already intubated and dying. [/QUOTE]
Insert quotes…
Verification
Post reply
Share this page
Facebook
Twitter
Reddit
Pinterest
Tumblr
WhatsApp
Email
Share
Link
Sponsors
Forums
General Health & Fitness
Health & Wellness
Coronavirus COVID-19 Update: Hydroxychloroquine and Other Treatments
This site uses cookies to help personalise content, tailor your experience and to keep you logged in if you register.
By continuing to use this site, you are consenting to our use of cookies.
Accept
Learn more…
Top