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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Considering TRT--Lab Results, Questions
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<blockquote data-quote="Cataceous" data-source="post: 221118" data-attributes="member: 38109"><p>With those numbers I would not consider conventional TRT yet. Your Vermeulen calculated free testosterone is 10.8 ng/dL, which isn't too bad if that's typical for you. The full reference range for Vermeulen FT is about 8-23. I view the healthy normal range as more like 10-20 ng/dL. Your total testosterone is low because of lowish SHBG. But free testosterone is more important, as that's what actually gets used.</p><p></p><p>The first step is to do some retesting. I'm guessing you're using Quest. You need to order <a href="https://testdirectory.questdiagnostics.com/test/test-detail/36170/testosterone-free-dialysis-and-total-ms?p=r&q=Testosterone,%20Free%20(Dialysis)%20and%20Total,%20MS&cc=MASTER" target="_blank">this test</a> for free and total testosterone. Discounted Labs offers it for a low price if you need to get it yourself. This test provides a different evaluation of free testosterone. Just as important is to retest estradiol with a <a href="https://testdirectory.questdiagnostics.com/test/results?q=Estradiol,%20Ultrasensitive,%20LC%2FMS" target="_blank">sensitive method</a>. The—presumed—immunoassay test you had can respond to C-reactive protein and give falsely-elevated values if CRP is also elevated. You need to sort this out. If CRP is high then that's a separate problem. If estradiol is truly that high relative to testosterone then micro-dosing an aromatase inhibitor could be viable as monotherapy.</p><p></p><p>If more accurate testing suggests free testosterone is low then you still have options short of full TRT. Regular TRT suppresses your own production of testosterone, disrupting many other hormones in the process, and sometimes causing new symptoms. A nasal gel product such as Natesto boosts testosterone with much less dispruption.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 221118, member: 38109"] With those numbers I would not consider conventional TRT yet. Your Vermeulen calculated free testosterone is 10.8 ng/dL, which isn't too bad if that's typical for you. The full reference range for Vermeulen FT is about 8-23. I view the healthy normal range as more like 10-20 ng/dL. Your total testosterone is low because of lowish SHBG. But free testosterone is more important, as that's what actually gets used. The first step is to do some retesting. I'm guessing you're using Quest. You need to order [URL='https://testdirectory.questdiagnostics.com/test/test-detail/36170/testosterone-free-dialysis-and-total-ms?p=r&q=Testosterone,%20Free%20(Dialysis)%20and%20Total,%20MS&cc=MASTER']this test[/URL] for free and total testosterone. Discounted Labs offers it for a low price if you need to get it yourself. This test provides a different evaluation of free testosterone. Just as important is to retest estradiol with a [URL='https://testdirectory.questdiagnostics.com/test/results?q=Estradiol,%20Ultrasensitive,%20LC%2FMS']sensitive method[/URL]. The—presumed—immunoassay test you had can respond to C-reactive protein and give falsely-elevated values if CRP is also elevated. You need to sort this out. If CRP is high then that's a separate problem. If estradiol is truly that high relative to testosterone then micro-dosing an aromatase inhibitor could be viable as monotherapy. If more accurate testing suggests free testosterone is low then you still have options short of full TRT. Regular TRT suppresses your own production of testosterone, disrupting many other hormones in the process, and sometimes causing new symptoms. A nasal gel product such as Natesto boosts testosterone with much less dispruption. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Considering TRT--Lab Results, Questions
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