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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Considering starting TRT although levels are not "clinically low" Feedback would be appreciated
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<blockquote data-quote="Cataceous" data-source="post: 201047" data-attributes="member: 38109"><p>I follow the general principle, but would point out that the short half-life of propionate can lead to excessive variation in serum testosterone. I was measuring around +/-50% variation about the mean with daily use, whereas healthy young men naturally top out at around +/-25%. It's possible to blend propionate with a longer ester to tune the amount of variation.</p><p></p><p></p><p>The prescribing information for Natesto doesn't address whether this product specifically has been shown to help with insulin resistance. But it notes that androgens in general can do this:</p><p></p><p style="margin-left: 20px"><em>Changes in insulin sensitivity or glycemic conrol may occur in patients treated with androgens. In diabetic patients, the metabolic effects of androgens may decrease blood glucose and, therefore, may necessitate a decrease in the dose of anti-diabetic medication.</em></p><p></p><p>I think you'd just need to try it. I don't see much to lose in doing this before going with conventional TRT.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 201047, member: 38109"] I follow the general principle, but would point out that the short half-life of propionate can lead to excessive variation in serum testosterone. I was measuring around +/-50% variation about the mean with daily use, whereas healthy young men naturally top out at around +/-25%. It's possible to blend propionate with a longer ester to tune the amount of variation. The prescribing information for Natesto doesn't address whether this product specifically has been shown to help with insulin resistance. But it notes that androgens in general can do this: [INDENT][I]Changes in insulin sensitivity or glycemic conrol may occur in patients treated with androgens. In diabetic patients, the metabolic effects of androgens may decrease blood glucose and, therefore, may necessitate a decrease in the dose of anti-diabetic medication.[/I][/INDENT] I think you'd just need to try it. I don't see much to lose in doing this before going with conventional TRT. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Considering starting TRT although levels are not "clinically low" Feedback would be appreciated
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