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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Considering starting TRT although levels are not "clinically low" Feedback would be appreciated
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<blockquote data-quote="madman" data-source="post: 200986" data-attributes="member: 13851"><p><strong>I order my own bloodwork a few times a year. I do the comprehensive ones and add in total and free test. My last one in December showed my <u>total to be 476 ng/dl and free 80 pg/ml</u>.</strong></p><p><strong></strong></p><p><strong><u>So..although my testosterone numbers aren't real low, and I don't feel overly lethargic or depressed..I feel some of the issues I described would be helped by going on TRT</u>.</strong></p><p></p><p></p><p>Judging by all the symptoms you state let alone having a TT 476 ng/dL your FT level is most likely sub-par/low depending on where your SHBG sits.</p><p></p><p>Although TT is important to know FT is what truly matters as it is the active unbound fraction of testosterone responsible for the positive effects.</p><p></p><p>Even though your TT 476 ng/dL is far from low we have no idea where your SHBG let alone FT truly sits as unfortunately it was most likely tested using an inaccurate assay (direct).</p><p></p><p>SHBG will have a significant impact on TT/FT.</p><p></p><p>The only way to know where your FT level truly sits is to have it tested using the most accurate assays such as the gold standard Equilibrium Dialysis or Ultrafiltration (next best).</p><p></p><p>I would definitely look into getting a full pre-trt panel done which includes the most accurate assays for TT/estradiol (LC/MS-MS) and FT (Equilibrium Dialysis or Ultrafiltration) before jumping to any conclusions!</p><p></p><p></p><p></p><p></p><p>You can use Nelsons discountedlabs to purchase such panels.</p><p></p><p>Many options available depending on what you are willing to spend.</p><p></p><p>[URL unfurl="true"]https://www.discountedlabs.com/catalog/product/view/id/54/s/pre-trt-male-hormone-wellness-panel/[/URL]</p></blockquote><p></p>
[QUOTE="madman, post: 200986, member: 13851"] [B]I order my own bloodwork a few times a year. I do the comprehensive ones and add in total and free test. My last one in December showed my [U]total to be 476 ng/dl and free 80 pg/ml[/U]. [U]So..although my testosterone numbers aren't real low, and I don't feel overly lethargic or depressed..I feel some of the issues I described would be helped by going on TRT[/U].[/B] Judging by all the symptoms you state let alone having a TT 476 ng/dL your FT level is most likely sub-par/low depending on where your SHBG sits. Although TT is important to know FT is what truly matters as it is the active unbound fraction of testosterone responsible for the positive effects. Even though your TT 476 ng/dL is far from low we have no idea where your SHBG let alone FT truly sits as unfortunately it was most likely tested using an inaccurate assay (direct). SHBG will have a significant impact on TT/FT. The only way to know where your FT level truly sits is to have it tested using the most accurate assays such as the gold standard Equilibrium Dialysis or Ultrafiltration (next best). I would definitely look into getting a full pre-trt panel done which includes the most accurate assays for TT/estradiol (LC/MS-MS) and FT (Equilibrium Dialysis or Ultrafiltration) before jumping to any conclusions! You can use Nelsons discountedlabs to purchase such panels. Many options available depending on what you are willing to spend. [URL unfurl="true"]https://www.discountedlabs.com/catalog/product/view/id/54/s/pre-trt-male-hormone-wellness-panel/[/URL] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Considering starting TRT although levels are not "clinically low" Feedback would be appreciated
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