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I just got my results back after my first two months on TRT, and things are not perfect, which doesn't exactly surprise me based on the way I've been feeling.


Background: 39 year old male, fit/athletic, no other health issues prior to starting TRT (aside from those associated with low T - I had most of those issues).


Pre-TRT:


TOTAL T: 333 ng/dl  (250-1100)

FREE T:  51.3 pg/dl  (35-155)

FSH:  3.3 mIU/ml  (1.7-8.6)

LH:  2.8 mIU/ml  (1.5-12.4)


Those were all of the tests done before starting TRT, including several more total T tests, all of which came back on the low end of normal. I was prescribed 200mg/g (20%) compounded cream, and I have been applying 1/2g daily.  No HCG, no AI.


Post-TRT:


TOTAL T:  795 ng/dl (264-916)

FREE T (DIRECT):  25.2 pg/ml (8.7-25.1) High

ESTRADIOL, SENSITIVE:  38.4 pg/ml (8-35)  High

HEMOGLOBIN:  17.3 g/dl  (13-17.7)

HEMATOCRIT:  50.5 %  (37.5-51) (not flagged as high but close)

SHBG:  26.9 nmol/L  (16.5-55.9)

TOTAL CHOLESTEROL:  203 mg/dl  (100-199) High

HDL:  56 mg/dl  (>39)

LDL:  122 mg/dl  (0-99)  High

PSA:  0.9 ng/ml  (0-4)

LH: 0.1 mIU/ml  (1.7-8.6) Low

DHEA:  337.3 ug/dl  (102.6-416.3)

TSH:  2.080 uIU/ml  (0.45-4.5)


Happy to provide more numbers for the various other tests that were run, but those are the highlights. My concerns are with hematocrit, estradiol, and cholesterol.


Experience:


I started out feeling amazing for the first few weeks. I have since heard this referred to on this board and elsewhere as the "honeymoon phase", and that sounds right to me. The next several weeks I would say that I felt moderately better than before TRT, but not as good as first few weeks. The last several weeks through present, I feel ok but hard saying if any better than pre-TRT. I noticed some fogginess, occasional low moods, mild discomfort around nipples that weren't there in the first few weeks - all of which I guessed even before seeing this may have been due to high E2.


My thoughts: as T levels increased, E2 increased and effectively offset any of the benefits I might have been feeling.


What thoughts or advice to you guys have on where to go from here? I'm in the process of switching to a more knowledgable TRT doc, but until then, I'd really appreciate any thoughts you guys might have.


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