ExcelMale
Menu
Home
What's new
Latest activity
Forums
New posts
Search forums
What's new
New posts
Latest activity
Videos
Lab Tests
Doctor Finder
Buy Books
About Us
Men’s Health Coaching
Log in
Register
What's new
Search
Search
Search titles only
By:
New posts
Search forums
Menu
Log in
Register
Navigation
Install the app
Install
More options
Contact us
Close Menu
Forums
Testosterone Replacement, Low T, HCG, & Beyond
Clomid for PCT, fertility or low T
Clomid & Testosterone: Why they don't work together - By Mike Gaiso
JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding.
You are using an out of date browser. It may not display this or other websites correctly.
You should upgrade or use an
alternative browser
.
Reply to thread
Message
<blockquote data-quote="Discovery41" data-source="post: 63849" data-attributes="member: 14237"><p>Fantastic responses, thank you all. I am just curious about the HCG desensitization on the leydig cells. I can find good research that fetal leydig cells do not become desensitized but not so much for adults. Anyone have thoughts or research on this? I like, but seem to disagree with what Chris Vettester said "<span style="color: #333333">Clomid is a SERM to stimulate natural LH production in the pituitary, whereas HCG is the LH analog in a bottle, no guesswork, you dial in your dose and it's guaranteed LH each and every time." In my mind, Clomid is "stimulating" a natural LH response from the pituitary. Whereas providing exogenous LH/FSH (HCG) to me would be kind of like TRT effects, only the leydig cells may decrease sensitivity (the AR's do not to such a great extent). In my mind, i like the idea that clomid stimulates LH and FSH production for the testes and for endogenous testosterone. It is used for off label fertility in males as well, so that suggest it works. </span></p><p><span style="color: #333333"></span></p><p><span style="color: #333333"></span></p></blockquote><p></p>
[QUOTE="Discovery41, post: 63849, member: 14237"] Fantastic responses, thank you all. I am just curious about the HCG desensitization on the leydig cells. I can find good research that fetal leydig cells do not become desensitized but not so much for adults. Anyone have thoughts or research on this? I like, but seem to disagree with what Chris Vettester said "[COLOR=#333333]Clomid is a SERM to stimulate natural LH production in the pituitary, whereas HCG is the LH analog in a bottle, no guesswork, you dial in your dose and it's guaranteed LH each and every time." In my mind, Clomid is "stimulating" a natural LH response from the pituitary. Whereas providing exogenous LH/FSH (HCG) to me would be kind of like TRT effects, only the leydig cells may decrease sensitivity (the AR's do not to such a great extent). In my mind, i like the idea that clomid stimulates LH and FSH production for the testes and for endogenous testosterone. It is used for off label fertility in males as well, so that suggest it works. [/COLOR] [/QUOTE]
Insert quotes…
Verification
Post reply
Share this page
Facebook
Twitter
Reddit
Pinterest
Tumblr
WhatsApp
Email
Share
Link
Sponsors
Forums
Testosterone Replacement, Low T, HCG, & Beyond
Clomid for PCT, fertility or low T
Clomid & Testosterone: Why they don't work together - By Mike Gaiso
This site uses cookies to help personalise content, tailor your experience and to keep you logged in if you register.
By continuing to use this site, you are consenting to our use of cookies.
Accept
Learn more…
Top