There are countless anecdotes, scientific research, etc, stating clomid is safe an effective in some cases to raise testosterone. As with any medications, it may cause side effects in some people. I've never been on clomid but I have been on enclomiphene for more than 6 months. Testosterone raised to 1100 ng/dL, no side effects, subjectively symptoms did not improve to the level I expected. By that was me, there are other people who have been on clomid for years a love it. Other's complain of eye floaters, getting emotional, feeling bloated, etc.
The same happens with TRT regardless of the method. If you search this forum, you'll see people quitting TRT after 1 year, 2 years, 4 years, etc. Some people complain of high blood pressure, decreased orgasm, etc. Others are pretty dialed in and love it. There's no single solution for everyone. You won't know until you try it (under medical supervision).
I think it's irresponsible to issue one-size-fits-all answers, particularly when new members come asking for help. Maybe it's just me, but one of the benefits I get from this forum is education. One line ideological zingers do not contribute to that.
Regarding to whether enclomiphene binds to multiple receptors in different organs, I'm still waiting for evidence to be provided to backup this statement, which I'd love to see. So far the literature I've reviewed claims it binds to ER receptors in the hypothalamus and pituitary. Some suspect it binds antagonistically to ER receptors in the breast tissue, and some theorize it must bind to ER receptors in the liver because enclomiphene tends to decrease IGF-1, but as far as I understand, it's just a hypothesis.
Take my advice: don't take advice from me.
