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General Health & Fitness
Nutrition and Supplements
Clinical Experience of a Diet Designed to Reduce Aging
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<blockquote data-quote="Nelson Vergel" data-source="post: 17110" data-attributes="member: 3"><p>J Appl Res. Author manuscript; available in PMC 2010 Mar 3.</p><p>Published in final edited form as:</p><p>J Appl Res. 2009 Jan 1; 9(4): 159–165.</p><p></p><p><strong>Clinical Experience of a Diet Designed to Reduce Aging</strong></p><p>Ron Rosedale, M.D., Eric C. Westman, M.D., M.H.S.,1 and John P. Konhilas, Ph.D.</p><p></p><p>Abstract</p><p></p><p>Objective:</p><p></p><p>Aging is associated with elevated levels of glucose, insulin, and triglycerides. Our objective was to assess the effect of a nutritional program designed to reduce these correlates of aging.</p><p></p><p>Design:</p><p></p><p>This is a retrospective chart review of patients attending an outpatient metabolic management program including a high-fat, adequate-protein, low-carbohydrate diet, nutritional supplementation and periodic individual visits. Outcomes measured at baseline and follow-up included body weight, fasting serum glucose, insulin, leptin, lipids, and thyroid hormone.</p><p></p><p>Results:</p><p></p><p>Thirty-one patients were identified with complete information. The mean age of patients was 57.6 ± 2.4 consisting of 53% female and 47% male patients. The average duration between follow up visits was 91.5 ± 8.5 days. Of the parameters measured at the follow-up visit, body weight, serum leptin, insulin, fasting glucose, triglyceride, and free T3 significantly decreased by 8.1 ± 0.8%, 48.2 ± 3.8%, 40.1 ± 4.7%, 7.6 ± 2.1%, 28.3 ± 5.7%, and 10.8 ± 1.8%, respectively. Furthermore, the triglyceride/high density lipoprotein ratio decreased from 5.1 ± 1.7 to 2.6 ± 0.5.</p><p></p><p>Conclusions:</p><p></p><p>In the context of an outpatient medical clinic, a high-fat, adequate-protein, low-carbohydrate diet with nutritional supplementation led to improvements in serum factors related to the aging process. Further research regarding this dietary approach and its relationship to aging is in order.</p><p></p><p></p><p>[ATTACH]1288[/ATTACH]</p><p></p><p>[ATTACH]1289[/ATTACH]</p></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 17110, member: 3"] J Appl Res. Author manuscript; available in PMC 2010 Mar 3. Published in final edited form as: J Appl Res. 2009 Jan 1; 9(4): 159–165. [B]Clinical Experience of a Diet Designed to Reduce Aging[/B] Ron Rosedale, M.D., Eric C. Westman, M.D., M.H.S.,1 and John P. Konhilas, Ph.D. Abstract Objective: Aging is associated with elevated levels of glucose, insulin, and triglycerides. Our objective was to assess the effect of a nutritional program designed to reduce these correlates of aging. Design: This is a retrospective chart review of patients attending an outpatient metabolic management program including a high-fat, adequate-protein, low-carbohydrate diet, nutritional supplementation and periodic individual visits. Outcomes measured at baseline and follow-up included body weight, fasting serum glucose, insulin, leptin, lipids, and thyroid hormone. Results: Thirty-one patients were identified with complete information. The mean age of patients was 57.6 ± 2.4 consisting of 53% female and 47% male patients. The average duration between follow up visits was 91.5 ± 8.5 days. Of the parameters measured at the follow-up visit, body weight, serum leptin, insulin, fasting glucose, triglyceride, and free T3 significantly decreased by 8.1 ± 0.8%, 48.2 ± 3.8%, 40.1 ± 4.7%, 7.6 ± 2.1%, 28.3 ± 5.7%, and 10.8 ± 1.8%, respectively. Furthermore, the triglyceride/high density lipoprotein ratio decreased from 5.1 ± 1.7 to 2.6 ± 0.5. Conclusions: In the context of an outpatient medical clinic, a high-fat, adequate-protein, low-carbohydrate diet with nutritional supplementation led to improvements in serum factors related to the aging process. Further research regarding this dietary approach and its relationship to aging is in order. [ATTACH=CONFIG]1288[/ATTACH] [ATTACH=CONFIG]1289[/ATTACH] [/QUOTE]
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Clinical Experience of a Diet Designed to Reduce Aging
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