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Nutrition and Supplements
Citrulline the new star for increasing nitric oxide
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<blockquote data-quote="madman" data-source="post: 189623" data-attributes="member: 13851"><p><strong>FIGURE 3 <span style="color: rgb(184, 49, 47)">The fate of orally ingested doses of Arg. </span>Ingested Arg is extracted and utilized during the first-pass metabolism of the splanchnic region <span style="color: rgb(184, 49, 47)">(intestinal and hepatic bed)</span>; Arg entered in the enterocytes is mainly confined into the partial urea cycle by both cytosolic and mitochondrial arginases to produce urea, ornithine, Cit, proline, polyamines, and CO2. The Arg delivered into the liver by the portal vein, is subjected to further catabolism via arginase I and is mainly converted to urea; within the splanchnic metabolism, a minor fraction of the ingested dose of Arg is converted to NO. Finally, about 10-30% of ingested doses are available for circulation; <span style="color: rgb(26, 188, 156)">OAT,</span> ornithine aminotransferase; <span style="color: rgb(26, 188, 156)">ODC,</span> ornithine decarboxylase; <span style="color: rgb(26, 188, 156)">OTC,</span> ornithine transcarbamylase; <span style="color: rgb(26, 188, 156)">GS,</span> glutamine synthetase </strong></p><p>[ATTACH=full]11303[/ATTACH]</p><p>[ATTACH=full]11304[/ATTACH]</p></blockquote><p></p>
[QUOTE="madman, post: 189623, member: 13851"] [B]FIGURE 3 [COLOR=rgb(184, 49, 47)]The fate of orally ingested doses of Arg. [/COLOR]Ingested Arg is extracted and utilized during the first-pass metabolism of the splanchnic region [COLOR=rgb(184, 49, 47)](intestinal and hepatic bed)[/COLOR]; Arg entered in the enterocytes is mainly confined into the partial urea cycle by both cytosolic and mitochondrial arginases to produce urea, ornithine, Cit, proline, polyamines, and CO2. The Arg delivered into the liver by the portal vein, is subjected to further catabolism via arginase I and is mainly converted to urea; within the splanchnic metabolism, a minor fraction of the ingested dose of Arg is converted to NO. Finally, about 10-30% of ingested doses are available for circulation; [COLOR=rgb(26, 188, 156)]OAT,[/COLOR] ornithine aminotransferase; [COLOR=rgb(26, 188, 156)]ODC,[/COLOR] ornithine decarboxylase; [COLOR=rgb(26, 188, 156)]OTC,[/COLOR] ornithine transcarbamylase; [COLOR=rgb(26, 188, 156)]GS,[/COLOR] glutamine synthetase [/B] [ATTACH type="full"]11303[/ATTACH] [ATTACH type="full"]11304[/ATTACH] [/QUOTE]
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General Health & Fitness
Nutrition and Supplements
Citrulline the new star for increasing nitric oxide
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