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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Chapter 12 - Hypothalamo-Pituitary Unit, Testis, and Male Accessory Organs
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<blockquote data-quote="tareload" data-source="post: 217272"><p>For those who want more info on Fig. 12.6B:</p><p></p><p>[URL unfurl="true"]https://journals.physiology.org/doi/prev/20171106-aop/abs/10.1152/ajpregu.00376.2003[/URL]</p><p></p><p>PDF:</p><p>[URL unfurl="true"]https://journals.physiology.org/doi/epdf/10.1152/ajpregu.00376.2003[/URL]</p><p></p><p>[ATTACH=full]19674[/ATTACH]</p><p></p><p>[ATTACH=full]19675[/ATTACH]</p><p>[ATTACH=full]19676[/ATTACH]</p><p></p><p></p><p>[ATTACH=full]19677[/ATTACH]</p><p></p><p>System of ODEs to describe the testosterone compartments:</p><p></p><p>[ATTACH=full]19679[/ATTACH]</p><p></p><p>If you work through the math and characteristic times one can show that our best understanding does not support the statement that lowering SHBG under the constraint of constant exogenous T ester results in higher free T (as [USER=38109]@Cataceous[/USER] has so eloquently stated many times). Instead if you magically wave your SHBG wand and lower SHBG (or take some oxandrolone) the free T will stay the same and Total T will decrease (measured at peak or trough with accurate method).</p></blockquote><p></p>
[QUOTE="tareload, post: 217272"] For those who want more info on Fig. 12.6B: [URL unfurl="true"]https://journals.physiology.org/doi/prev/20171106-aop/abs/10.1152/ajpregu.00376.2003[/URL] PDF: [URL unfurl="true"]https://journals.physiology.org/doi/epdf/10.1152/ajpregu.00376.2003[/URL] [ATTACH type="full" alt="1644523348588.png"]19674[/ATTACH] [ATTACH type="full" alt="1644523366903.png"]19675[/ATTACH] [ATTACH type="full" alt="1644523505834.png"]19676[/ATTACH] [ATTACH type="full" alt="1644524050852.png"]19677[/ATTACH] System of ODEs to describe the testosterone compartments: [ATTACH type="full" alt="1644524666705.png"]19679[/ATTACH] If you work through the math and characteristic times one can show that our best understanding does not support the statement that lowering SHBG under the constraint of constant exogenous T ester results in higher free T (as [USER=38109]@Cataceous[/USER] has so eloquently stated many times). Instead if you magically wave your SHBG wand and lower SHBG (or take some oxandrolone) the free T will stay the same and Total T will decrease (measured at peak or trough with accurate method). [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Chapter 12 - Hypothalamo-Pituitary Unit, Testis, and Male Accessory Organs
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