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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
CDC STANDARDIZED TOTAL T and ESTRADIOL ASSAYS and soon to be FREE TESTOSTERONE!
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<blockquote data-quote="madman" data-source="post: 133507" data-attributes="member: 13851"><p><a href="https://www.aacc.org/publications/cln/articles/2018/october/how-the-cdc-clinical-standardization-programs-are-improving-hormone-tests" target="_blank">How the CDC Clinical Standardization Programs Are Improving Hormone Tests - AACC.org</a></p><p></p><p><span style="font-size: 22px"><strong>WHAT PROGRESS HAS CDC MADE WITH STANDARDIZING TOTAL TESTOSTERONE AND ESTRADIOL TESTS?</strong></span></p><p></p><p></p><p></p><p><em>Since HoSt began in 2010, CDC has had more than 350 participants in 15 countries. Participants have shown measurable improvements for both total testosterone (TT) and estradiol (E2). <strong>Specifically, the among-laboratory bias has decreased from 16.5% in 2007 to 2.8% in 2017 for TT and from<span style="color: rgb(184, 49, 47)"> 54.8% in 2012 to 13.9% in 2017 for E2</span></strong></em><span style="color: rgb(184, 49, 47)"><em>. </em></span><em>Not only has bias improved, but data from proficiency testing programs also show that standardized testosterone assays are more accurate and consistent compared to non-standardized assays.</em></p><p><em></em></p><p><em></em></p><p><em>Recently, CDC CSP also collaborated with the Endocrine Society and PATH to develop reference ranges for testosterone in non-obese men ages 19-39 years old. These reference ranges are now part of an Endocrine Society clinical practice guideline and according to this guideline can be used by laboratory tests standardized to CDC’s criteria.</em></p><p></p><p></p><p></p><p>[URL unfurl="true"]https://www.endocrine.org/clinical-practice-guidelines/testosterone-therapy[/URL]</p><p></p><p></p><p></p><p><span style="font-size: 22px"><strong>WHAT ARE THE NEXT STEPS NOW THAT CDC HAS RECEIVED ADDITIONAL FUNDING FROM CONGRESS FOR HARMONIZATION IN 2018?</strong></span></p><p></p><p><a href="https://www.aacc.org/publications/cln/articles/2018/may/congress-funds-aacc-led-harmonization-initiative" target="_blank"><em>This is the first time CDC has received dedicated funding from Congress to improve the quality and reliability of diagnostic tests for hormones.</em></a><em> With these funds, CDC CSP plans to increase in size and scope through the addition of new programs, such as the Accuracy-based Monitoring Program for routine laboratories, and new biomarkers such as parathyroid hormones, free thyroxine, <strong><span style="color: rgb(184, 49, 47)">and free testosterone.</span></strong> CDC CSP will continue to work with stakeholders and participants to reduce calibration bias and individual sample bias in order to enhance patient care and public health.</em></p><p></p><p></p><p></p><p></p><p>I and many others will be looking forward to the <strong><span style="color: rgb(184, 49, 47)">FREE TESTOSTERONE </span><span style="color: rgb(0, 0, 0)">CDC (HoSt) PROGRAM!</span></strong></p></blockquote><p></p>
[QUOTE="madman, post: 133507, member: 13851"] [URL='https://www.aacc.org/publications/cln/articles/2018/october/how-the-cdc-clinical-standardization-programs-are-improving-hormone-tests']How the CDC Clinical Standardization Programs Are Improving Hormone Tests - AACC.org[/URL] [SIZE=22px][B]WHAT PROGRESS HAS CDC MADE WITH STANDARDIZING TOTAL TESTOSTERONE AND ESTRADIOL TESTS?[/B][/SIZE] [I]Since HoSt began in 2010, CDC has had more than 350 participants in 15 countries. Participants have shown measurable improvements for both total testosterone (TT) and estradiol (E2). [B]Specifically, the among-laboratory bias has decreased from 16.5% in 2007 to 2.8% in 2017 for TT and from[COLOR=rgb(184, 49, 47)] 54.8% in 2012 to 13.9% in 2017 for E2[/COLOR][/B][/I][COLOR=rgb(184, 49, 47)][I]. [/I][/COLOR][I]Not only has bias improved, but data from proficiency testing programs also show that standardized testosterone assays are more accurate and consistent compared to non-standardized assays. Recently, CDC CSP also collaborated with the Endocrine Society and PATH to develop reference ranges for testosterone in non-obese men ages 19-39 years old. These reference ranges are now part of an Endocrine Society clinical practice guideline and according to this guideline can be used by laboratory tests standardized to CDC’s criteria.[/I] [URL unfurl="true"]https://www.endocrine.org/clinical-practice-guidelines/testosterone-therapy[/URL] [SIZE=22px][B]WHAT ARE THE NEXT STEPS NOW THAT CDC HAS RECEIVED ADDITIONAL FUNDING FROM CONGRESS FOR HARMONIZATION IN 2018?[/B][/SIZE] [URL='https://www.aacc.org/publications/cln/articles/2018/may/congress-funds-aacc-led-harmonization-initiative'][I]This is the first time CDC has received dedicated funding from Congress to improve the quality and reliability of diagnostic tests for hormones.[/I][/URL][I] With these funds, CDC CSP plans to increase in size and scope through the addition of new programs, such as the Accuracy-based Monitoring Program for routine laboratories, and new biomarkers such as parathyroid hormones, free thyroxine, [B][COLOR=rgb(184, 49, 47)]and free testosterone.[/COLOR][/B] CDC CSP will continue to work with stakeholders and participants to reduce calibration bias and individual sample bias in order to enhance patient care and public health.[/I] I and many others will be looking forward to the [B][COLOR=rgb(184, 49, 47)]FREE TESTOSTERONE [/COLOR][COLOR=rgb(0, 0, 0)]CDC (HoSt) PROGRAM![/COLOR][/B] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
CDC STANDARDIZED TOTAL T and ESTRADIOL ASSAYS and soon to be FREE TESTOSTERONE!
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