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I've never refrigerated iit or have been instructed to. I just now read this:

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Storing and Traveling With CAVERJECT IMPULSE:

Unmixed CAVERJECT IMPULSE should be stored at room temperature (59º F to 86º F) and should not be refrigerated or frozen.


http://www.caverject.com/about-caverject-impulse


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The Caverject I use has to be mixed by turning the threaded plunger until a powder mixes with a liquid. I get three boxes with two plungers in each box for a total of six.


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