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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
CARDIOVASCULAR AND METABOLIC ACTIONS OF THE ANDROGENS
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<blockquote data-quote="madman" data-source="post: 239215" data-attributes="member: 13851"><p><strong>Fig. 5. <u>Effects of gonadal dysfunction on metabolic function, abdominal obesity, and muscle mass in men vs. women</u>. The Y-axis represents the percentage of men or women in the general population, the X-axis represents serum levels of total TES. TES levels in normal men are 10-30 fold higher than in normal women (note blue vs. pink arrows on X-axis). Androgen excess in women (e.g., development of PCOS) increases abdominal adiposity, resulting in an unfavorable metabolic profile (MetS); whereas in men, much higher normal androgen levels protect against MetS by increasing lean and skeletal muscle mass and reducing abdominal adiposity to levels equivalent to those of normal women. The loss of androgen in men results in a marked decline in lean and skeletal muscle mass and increased abdominal adiposity, also resulting in MetS. <u>The grey area in the center represents the common ground of metabolic dysfunction and development of MetS and T2DM, major risk factors for the development of CVD in both females and males, hence it has been described as the “metabolic valley of death” by Schiffer et al</u> [50]. Redrawn from Morreale-Escobar et al., 2014 [49].</strong></p><p><strong>[ATTACH=full]26930[/ATTACH]</strong></p></blockquote><p></p>
[QUOTE="madman, post: 239215, member: 13851"] [B]Fig. 5. [U]Effects of gonadal dysfunction on metabolic function, abdominal obesity, and muscle mass in men vs. women[/U]. The Y-axis represents the percentage of men or women in the general population, the X-axis represents serum levels of total TES. TES levels in normal men are 10-30 fold higher than in normal women (note blue vs. pink arrows on X-axis). Androgen excess in women (e.g., development of PCOS) increases abdominal adiposity, resulting in an unfavorable metabolic profile (MetS); whereas in men, much higher normal androgen levels protect against MetS by increasing lean and skeletal muscle mass and reducing abdominal adiposity to levels equivalent to those of normal women. The loss of androgen in men results in a marked decline in lean and skeletal muscle mass and increased abdominal adiposity, also resulting in MetS. [U]The grey area in the center represents the common ground of metabolic dysfunction and development of MetS and T2DM, major risk factors for the development of CVD in both females and males, hence it has been described as the “metabolic valley of death” by Schiffer et al[/U] [50]. Redrawn from Morreale-Escobar et al., 2014 [49]. [ATTACH type="full"]26930[/ATTACH][/B] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
CARDIOVASCULAR AND METABOLIC ACTIONS OF THE ANDROGENS
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