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General Peptide Use & Information
cardarine use , stomach issues/blood sugar, Who has used it?
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<blockquote data-quote="BigTex" data-source="post: 219156" data-attributes="member: 43589"><p>Yea, they gave those poor rats a very high dose for a very long period of time. Not something a human would need. GW-501516 developed by Glaxo Smith Kline to prevent prostate and breast tumors. The drug was manufactured in 1992 with an objective to increase HDL and reduce LDL cholesterol in the body. </p><p></p><p>I have used it quite a few times in the past and feel it did help with fat burning some and definitely helps with aerobic capacity. Most likely why it is a banned substance in the IOC</p><p></p><p>I know of two guys that did pre- and post blood work and found of it seem to lower lipid values.</p><p></p><p>Ooi EM, Watts GF, Sprecher DL, Chan DC, Barrett PH. <strong> Mechanism of action of a peroxisome proliferator-activated receptor (PPAR)-delta agonist on lipoprotein metabolism in dyslipidemic subjects with central obesity.</strong> J Clin Endocrinol Metab. 2011 Oct;96(10):E1568-76. doi: 10.1210/jc.2011-1131. Epub 2011 Aug 3. PMID: 21816786.</p><p></p><p><strong>Conclusions:</strong> GW501516 increased the hepatic removal of VLDL particles, which might have resulted from decreased apoC-III concentration. GW501516 increased apoA-II production, resulting in an increased concentration of LpA-I:A-II particles. This study elucidates the mechanism of action of this PPAR-δ agonist on lipoprotein metabolism and supports its potential use in treating dyslipidemia in obesity.</p><p></p><p>Yes PEG 400 is used in used to cause raw powders to go into suspension in liquid products whose molecular weight is between 232 to 594. The molecular weight of GW-501516 is 453.50</p></blockquote><p></p>
[QUOTE="BigTex, post: 219156, member: 43589"] Yea, they gave those poor rats a very high dose for a very long period of time. Not something a human would need. GW-501516 developed by Glaxo Smith Kline to prevent prostate and breast tumors. The drug was manufactured in 1992 with an objective to increase HDL and reduce LDL cholesterol in the body. I have used it quite a few times in the past and feel it did help with fat burning some and definitely helps with aerobic capacity. Most likely why it is a banned substance in the IOC I know of two guys that did pre- and post blood work and found of it seem to lower lipid values. Ooi EM, Watts GF, Sprecher DL, Chan DC, Barrett PH. [b] Mechanism of action of a peroxisome proliferator-activated receptor (PPAR)-delta agonist on lipoprotein metabolism in dyslipidemic subjects with central obesity.[/b] J Clin Endocrinol Metab. 2011 Oct;96(10):E1568-76. doi: 10.1210/jc.2011-1131. Epub 2011 Aug 3. PMID: 21816786. [b]Conclusions:[/b] GW501516 increased the hepatic removal of VLDL particles, which might have resulted from decreased apoC-III concentration. GW501516 increased apoA-II production, resulting in an increased concentration of LpA-I:A-II particles. This study elucidates the mechanism of action of this PPAR-δ agonist on lipoprotein metabolism and supports its potential use in treating dyslipidemia in obesity. Yes PEG 400 is used in used to cause raw powders to go into suspension in liquid products whose molecular weight is between 232 to 594. The molecular weight of GW-501516 is 453.50 [/QUOTE]
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Peptide Forums (GHRH, Sermorelin, etc)
General Peptide Use & Information
cardarine use , stomach issues/blood sugar, Who has used it?
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