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Testosterone Replacement, Low T, HCG, & Beyond
When Testosterone Is Not Enough
Can you take non-daily 10mg Cialis, daily?
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<blockquote data-quote="madman" data-source="post: 249759" data-attributes="member: 13851"><p>Yes, one could try taking a maximum daily dose of 10 mg only if they have not responded to lower doses of 2.5-5 mg.</p><p></p><p>Jumping in at 10 mg daily would basically be overkill and you would be pissing your money away.</p><p></p><p>Look over the PK and blood levels achieved.</p><p></p><p>Need to get out of that more is better mentality.</p><p></p><p>The starting dose for daily tadalafil is 2.5-5 mg and most men are started on 5mg.</p><p></p><p>Far from common, one would need 10 mg daily.</p><p></p><p>Take home point here.</p><p></p><p><em><strong>*the efficacy and tolerability of 5 mg tadalafil taken daily appear to be comparable to the efficacy and tolerability of 20 mg taken on-demand or every other day</strong></em></p><p></p><p></p><p><strong><em>post #10</em></strong></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/cialis-vs-viagra-heart-rate-side-effects.24513/#post-213399[/URL]</p><p></p><p><em><strong>*Historically, tadalafil has been taken on-demand at doses of 10 or 20 mg.</strong> The ability of a drug to reach steady-state results from the frequency of administration relative to half-life. The 17.5-hour half-life of tadalafil makes it an ideal candidate for once-daily therapy because steady-state plasma concentrations are attained within five days of daily dosing, and exposure is approximately 1.6-fold greater than after a single dose [11].<strong> If <u>5-mg and 10-mg doses are taken daily</u>, a cumulative tadalafil plasma exposure equivalent to <u>on-demand doses of 8 mg and 16 mg</u>, respectively, could be achieved in a few days</strong></em></p><p><em><strong></strong></em></p><p><em><strong></strong></em></p><p><em><strong>*the efficacy and tolerability of 5 mg tadalafil taken daily appear to be comparable to the efficacy and tolerability of 20 mg taken on-demand or every other day. Further studies that address this comparison could be useful for clinicians</strong></em></p><p></p><p></p><p></p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/help-with-urinary-issues-while-on-trt-bph-or-overactive-pelvic-floor-muscle.22468/[/URL]</p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/tadalafil-cialis-minimum-effective-dose.22853/[/URL]</p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/penis-sensitivity-issue.21534/page-3#post-197331[/URL]</p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/the-4-pillars-of-mens-health-and-expectations-on-male-sexuality.23363/[/URL]</p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/to-anyone-taking-cialis-daily-%E2%80%94-did-you-develop-a-dependence-on-it.23556/#post-202385[/URL]</p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/anyone-used-using-calcium-d-glucarate-for-estrogen-control.23717/#post-204178[/URL]</p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/targeting-of-pde5-for-preservation-of-penile-health.24924/#post-218542[/URL]</p></blockquote><p></p>
[QUOTE="madman, post: 249759, member: 13851"] Yes, one could try taking a maximum daily dose of 10 mg only if they have not responded to lower doses of 2.5-5 mg. Jumping in at 10 mg daily would basically be overkill and you would be pissing your money away. Look over the PK and blood levels achieved. Need to get out of that more is better mentality. The starting dose for daily tadalafil is 2.5-5 mg and most men are started on 5mg. Far from common, one would need 10 mg daily. Take home point here. [I][B]*the efficacy and tolerability of 5 mg tadalafil taken daily appear to be comparable to the efficacy and tolerability of 20 mg taken on-demand or every other day[/B][/I] [B][I]post #10[/I][/B] [URL unfurl="true"]https://www.excelmale.com/forum/threads/cialis-vs-viagra-heart-rate-side-effects.24513/#post-213399[/URL] [I][B]*Historically, tadalafil has been taken on-demand at doses of 10 or 20 mg.[/B] The ability of a drug to reach steady-state results from the frequency of administration relative to half-life. The 17.5-hour half-life of tadalafil makes it an ideal candidate for once-daily therapy because steady-state plasma concentrations are attained within five days of daily dosing, and exposure is approximately 1.6-fold greater than after a single dose [11].[B] If [U]5-mg and 10-mg doses are taken daily[/U], a cumulative tadalafil plasma exposure equivalent to [U]on-demand doses of 8 mg and 16 mg[/U], respectively, could be achieved in a few days *the efficacy and tolerability of 5 mg tadalafil taken daily appear to be comparable to the efficacy and tolerability of 20 mg taken on-demand or every other day. Further studies that address this comparison could be useful for clinicians[/B][/I] [URL unfurl="true"]https://www.excelmale.com/forum/threads/help-with-urinary-issues-while-on-trt-bph-or-overactive-pelvic-floor-muscle.22468/[/URL] [URL unfurl="true"]https://www.excelmale.com/forum/threads/tadalafil-cialis-minimum-effective-dose.22853/[/URL] [URL unfurl="true"]https://www.excelmale.com/forum/threads/penis-sensitivity-issue.21534/page-3#post-197331[/URL] [URL unfurl="true"]https://www.excelmale.com/forum/threads/the-4-pillars-of-mens-health-and-expectations-on-male-sexuality.23363/[/URL] [URL unfurl="true"]https://www.excelmale.com/forum/threads/to-anyone-taking-cialis-daily-%E2%80%94-did-you-develop-a-dependence-on-it.23556/#post-202385[/URL] [URL unfurl="true"]https://www.excelmale.com/forum/threads/anyone-used-using-calcium-d-glucarate-for-estrogen-control.23717/#post-204178[/URL] [URL unfurl="true"]https://www.excelmale.com/forum/threads/targeting-of-pde5-for-preservation-of-penile-health.24924/#post-218542[/URL] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
When Testosterone Is Not Enough
Can you take non-daily 10mg Cialis, daily?
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