I'm currently a 49-year-old male who is been diagnosed with low testosterone ,  I currently take warfarin because I have factor five Leiden, have been dose stable for 8 years 7.5 mg ave per days 30 days, 5 mg daily with 1/2 of 5 mg every other day (pt/inr 2.4) this is tested at home and at dr office, I have been through 7 physicians and endocrinologists.  All have remove me from their patient group because they feel issuing testosterone for treatment  (255 (bottom 5 %) tested 6 days ago), is too risky stating lack of research on  therapeutic warfarin patients.  all of the research that I am able to find via the Internet and medical journals shows that testosterone therapy increases hypercoagulability with warfarin patients ,  which would indicate a lower level of warfarin needed should testosterone therapy be started  to remain therapeutic ,  I have lived with this condition now for eight years I have a very good understanding of warfarin therapy along with my condition. I'm currently  fighting an uphill battle to find a physician that is willing to treat the condition, thyroid has been tested and ruled out , tumor ruled out, enlarged prostate has been ruled out . Looking for help for a better quality of life not only for myself but my wife.  Symptoms of low testosterone started showing up approximately six years ago they involved night sweats, lack of motivation , lack of sexual drive , muscle loss , slowed hair growth, Excessive weight gain (cortisol levels are at the high-end of the gray area) I also take lisinopril 20/12.5  for elevated blood pressure which started a year after warfarin therapy ,  A1 C levels also show elevated approximately one year after starting warfarin therapy, D3 deficiency also started one year after warfarin therapy.