Does it make sense to take Metformin 3 x's a day? I have a prescription for 500 mg. I have been taking 1000 in the evening and 1000 in the morning for my cardio days and 500 mg on the days I do weights. I've been told that taking Metformin the night before and in the morning before cardio is the best way to lose weight in a low insulin, fasted state.
I'm wondering if I should just take 500 mg morning, noon, and night? Any thoughts or does it not matter.