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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Can estrogen crash cause desensitization/knock out of the estrogen receptor - lets discuss!
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<blockquote data-quote="nurselyfe" data-source="post: 120285" data-attributes="member: 16355"><p>Wow thanks for telling us how you feel about the phenomenon. Since we're talking about feelings, before May 23rd, 2017. Crashing estrogen to me was no big deal. What was so bad about it? Dry joints? Vascularity? Frequent urination? Dry looking physique? Sometimes no pump. For me, I never had anxiety as a symptom. It'd clear up within 4-6 days maximum. Never once did I cry and say well I am screwed because I am well aware of how the body works and it will produce more estrogen if you give it some time. Well, May 23rd, 2017 happened. Every single symptom I have now appeared within hours, never went away, and only got worse. Being a medical professional as well, during that time not once did I say I was screwed or had pessimistic thoughts because like your experiences, I always felt fine if I gave it time, EVEN though I was experiencing side effects that I had never experienced in my entire life. Well time went on, even with an E2 level of 17, 60, 89, nothing got better. In fact it only kept getting worse. It's now over a year later, and my condition is a million times worse than it was last summer despite being on a stable protocol for a year and no arimidex since last August. I have a normal E2 level verified by the estrogen sensitive test, and I do not even have my usual low estrogen symptoms, but rather these disturbing symptoms I have never ever had before. But I do know it's related to estrogen because of the manner in which what made my symptoms become worse. I am on the same protocol I have always been on and under Dr. Sayas care whom has said himself he does have reason to believe something else is going on here but neither of us have an answer due to my blood work coming back absolutely fine.</p><p></p><p>With that being said, I think 99% of the guys here who freak about Low E2 and "permanent damage" need to relax. Not once did I ever freak out and I've crashed my E2 many many times very bad. However, I never anticipated on this happening nor do I think it will happen to many more people. There is clearly a genetic susceptibility to this. Vitamin C, while most of what you say I agree with that some of these guys need to chill out due the downward spiral low E2 may bring them, I would also suggest you get off your high horse and understand you're still young in your profession and medicine is even younger in relevance; you do not know everything. Myself, and possibly 2-3 others here have something else going on that has not been elucidated in medicine yet, so your argument that you cannot find anything in the literature is null. Luckily, working with several others I have found some interesting things in the literature that may suggest what is going on on the molecular level to cause some of my symptoms such as muscular dystrophy, gastroparesis, full body hair loss, dry hair, dry skin, etc. Still working diligently on my end to do whatever I can to figure this out because I am well aware what is normal and what is not.</p><p></p><p>Edit: Before you mention the whole dopamine thing, I am not one who thinks theres anything wrong with my dopamine neurons dying or whatever odd theories people are proposing here. Keep me out of it.</p></blockquote><p></p>
[QUOTE="nurselyfe, post: 120285, member: 16355"] Wow thanks for telling us how you feel about the phenomenon. Since we're talking about feelings, before May 23rd, 2017. Crashing estrogen to me was no big deal. What was so bad about it? Dry joints? Vascularity? Frequent urination? Dry looking physique? Sometimes no pump. For me, I never had anxiety as a symptom. It'd clear up within 4-6 days maximum. Never once did I cry and say well I am screwed because I am well aware of how the body works and it will produce more estrogen if you give it some time. Well, May 23rd, 2017 happened. Every single symptom I have now appeared within hours, never went away, and only got worse. Being a medical professional as well, during that time not once did I say I was screwed or had pessimistic thoughts because like your experiences, I always felt fine if I gave it time, EVEN though I was experiencing side effects that I had never experienced in my entire life. Well time went on, even with an E2 level of 17, 60, 89, nothing got better. In fact it only kept getting worse. It's now over a year later, and my condition is a million times worse than it was last summer despite being on a stable protocol for a year and no arimidex since last August. I have a normal E2 level verified by the estrogen sensitive test, and I do not even have my usual low estrogen symptoms, but rather these disturbing symptoms I have never ever had before. But I do know it's related to estrogen because of the manner in which what made my symptoms become worse. I am on the same protocol I have always been on and under Dr. Sayas care whom has said himself he does have reason to believe something else is going on here but neither of us have an answer due to my blood work coming back absolutely fine. With that being said, I think 99% of the guys here who freak about Low E2 and "permanent damage" need to relax. Not once did I ever freak out and I've crashed my E2 many many times very bad. However, I never anticipated on this happening nor do I think it will happen to many more people. There is clearly a genetic susceptibility to this. Vitamin C, while most of what you say I agree with that some of these guys need to chill out due the downward spiral low E2 may bring them, I would also suggest you get off your high horse and understand you're still young in your profession and medicine is even younger in relevance; you do not know everything. Myself, and possibly 2-3 others here have something else going on that has not been elucidated in medicine yet, so your argument that you cannot find anything in the literature is null. Luckily, working with several others I have found some interesting things in the literature that may suggest what is going on on the molecular level to cause some of my symptoms such as muscular dystrophy, gastroparesis, full body hair loss, dry hair, dry skin, etc. Still working diligently on my end to do whatever I can to figure this out because I am well aware what is normal and what is not. Edit: Before you mention the whole dopamine thing, I am not one who thinks theres anything wrong with my dopamine neurons dying or whatever odd theories people are proposing here. Keep me out of it. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Can estrogen crash cause desensitization/knock out of the estrogen receptor - lets discuss!
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